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Different effects of strenuous eccentric exercise on the accumulation of neutrophils in muscle in women and men. | LitMetric

Different effects of strenuous eccentric exercise on the accumulation of neutrophils in muscle in women and men.

Eur J Appl Physiol

School of Rehabilitation Sciences, University of British Columbia, T325 2211 Wesbrook Mall, Vancouver, BC V6T 2B5, Canada.

Published: January 2000

AI Article Synopsis

  • The study examined sex differences in delayed onset muscle soreness (DOMS), muscle torque, and neutrophil accumulation following eccentric exercise in 22 subjects (10 females, 12 males).
  • Blood samples were taken to label neutrophils with technetium-99m (Tc-99m) and re-infused before participants performed 300 eccentric repetitions of their quadriceps muscles.
  • Results showed greater neutrophil presence and increased DOMS in females compared to males post-exercise, indicating that sex influences muscle response to eccentric exercises and highlighting the need for further research in this area.

Article Abstract

The purpose of this study was to evaluate the sex differences in delayed onset muscle soreness (DOMS), torque, and accumulation of technetium-99m (Tc-99m) neutrophils in eccentric-exercised muscle. A group of 10 female and 12 male subjects took part in this study. The subjects completed a pre-test using the descriptor differential scale (DDS) to describe DOMS, and tests of concentric and eccentric torque of the right quadriceps. A volume of 100 ml of blood was taken by venipuncture for neutrophil labelling in the early morning of the exercise day. The Tc-99m neutrophils were re-infused intravenously before the eccentric exercise. The exercise stimulus consisted of 300 eccentric repetitions of the right quadriceps muscles. Radionuclide images of both quadriceps muscles (lateral views) were taken at 2 and 4 h. The DDS, and concentric and eccentric torques of the quadriceps were subsequently evaluated at 0 h, 2, 4, 20 and 24 h post-exercise. The presence of Tc-99m neutrophils was greater in the exercised leg than the non-exercised leg at 2 and 4 h post-exercise (P

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http://dx.doi.org/10.1007/PL00013796DOI Listing

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