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Accuracy of transthoracic echocardiography in diagnosis of cardiac myxoma: single center experience.
Radiol Oncol
January 2025
1Department of Cardiology, University Medical Center Ljubljana, Ljubljana, Slovenia.
Background: The differential diagnosis of cardiac myxomas (CM), the most common benign primary cardiac tumors, is broad and a thorough diagnostic workup is required to establish accurate diagnosis prior to surgical resection. Transthoracic echocardiography (TTE) is usually the first imaging modality used for diagnosis of suspected CM. In a single tertiary centre study, we sought to determine the accuracy, sensitivity, and specificity of TTE in the diagnosis of CM and to determine echocardiographic characteristics indicative of CM.
View Article and Find Full Text PDFGiant Cardiac Myxoma as a Cause of Stroke.
JACC Case Rep
December 2024
Cardiology Department, District Hospital of Santarém, Santarém, Portugal.
Cardiac myxomas are the most common primary intracardiac tumors and are histologically benign. However, they are potentially dangerous because of the risk of systemic embolism. Echocardiography is the key diagnostic tool for atrial myxomas, allowing for the identification of the tumor, as well as determining its location, shape, size, and connections with adjacent cardiac structures.
View Article and Find Full Text PDFlncRNA, miRNA, and mRNA of plasma and tumor-derived exosomes of cardiac myxoma-related ischaemic stroke.
Sci Data
January 2025
Department of Neurology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.
Cardiac myxoma (CM) is an important aetiology of stroke in young adults, and its diagnosis is difficult in patients having stroke because of the lack of diagnostic biomarkers. Tumour-derived exosomes play a crucial role in tumour growth, metastasis, immune regulation, and monitor disease development. Hence,we established an RNA-sequencing dataset for long non-coding RNA (lncRNA), microRNA (miRNA), and messenger RNA (mRNA) in the plasma and tumour-derived exosomes from four patients with cardiac myxoma-related ischaemic stroke (CM-IS) and six patients with cardiac myxoma without ischaemic stroke (non-IS CM).
View Article and Find Full Text PDFCRISPR detection of cardiac tumor-associated microRNAs.
Mol Biol Rep
January 2025
Department of Cardiology, Ganzhou People's Hospital, Ganzhou, Jiangxi, China.
As multiple imaging modalities cannot reliably diagnose cardiac tumors, the molecular approach offers alternative ways to detect rare ones. One such molecular approach is CRISPR-based diagnostics (CRISPR-Dx). CRISPR-Dx enables visual readout, portable diagnostics, and rapid and multiplex detection of nucleic acids such as microRNA (miRNA).
View Article and Find Full Text PDFNeurological complications of left atrial myxoma: a case report on stroke with left atrial myxoma and postoperative brain metastasis and cerebral aneurysm.
Front Neuroimaging
December 2024
Department of Medical Imaging, Wuhan Pulmonary Hospital, Wuhan, China.
Atrial myxoma is a rare benign tumor that can cause a variety of complications, including cerebral infarction. We present a case of a 52-year-old female patient who developed cerebral infarction caused by an atrial myxoma. The patient underwent successful surgical resection of the tumor, and the infarction was managed accordingly.
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