The immunostimulating activity of saponin-containing extract of Saponaria officinalis has been studied. Use of an S. officinalis extract in a concentration close to the critical concentration of saponin micella formation increased the immunogenicity of viral glycoproteins. The immunogenicity of glycoprotein complexes with S. officinalis was higher than the immunogenicity of intact virus and micellae of purified glycoproteins and was comparable to that of glycoprotein complexes with Quil A glycoside.
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