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The antihypertensive efficacy of a quadruple single-pill combination in patients with resistant hypertension: study protocol for a randomized, open-label, crossover trial.
Trials
January 2025
Cardiology Department, West China Hospital, Sichuan University, Chengdu, Sichuan Province, 610041, People's Republic of China.
Background: Resistant hypertension (RH) is defined as uncontrolled blood pressure (BP) despite treatment with at least three or more antihypertensive agents. Compelling evidence has shown that such a population has a greater risk of cardiovascular events as well as mortality. Although mineralocorticoid receptor antagonists (MRAs) have been shown to be an effective fourth-line treatment for RH, a significant proportion of RH patients do not achieve their blood pressure target.
View Article and Find Full Text PDFHow Should Clinicians Discuss Deprescribing with Caregivers of Older Adults Living with Dementia? A Qualitative Study.
Drugs Aging
January 2025
Division of Pharmaceutical Outcomes and Policy, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Background: Preventive medications are potential targets for deprescribing in older adults with dementia as goals of care change from preventive to palliative. Yet, prescribers lack communication guidance to address deprescribing.
Objective: Using bisphosphonates as a case example, we sought to characterize and compare communication preferences of prescribers and family/informal caregivers regarding deprescribing.
The impact of welfare technology on care ethics: a qualitative analysis of healthcare professionals and managers' experiences with welfare technologies.
BMC Health Serv Res
January 2025
Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
Background: Providing healthcare for the elderly population is challenging due to a shortage of staff. The challenge is addressed by increased use of technology. The article explores the impact of welfare technology on healthcare personnel's care ethical considerations in Norway's primary healthcare sector.
View Article and Find Full Text PDFExploring the availability and accessibility of medication abortion pills in Delhi, India: A mystery client study in community pharmacies.
Contraception
November 2024
Faculty of Health Sciences, University of Ottawa, Ottawa, ON, Canada; Collaborative for Interdisciplinary Global Abortion Research, Ottawa, ON, Canada. Electronic address:
Objectives: Although medication abortion drugs technically require a prescription in India, research suggests that they are often available directly from pharmacies. We conducted a mystery client study in the capital city of Delhi to explore the availability, accessibility, and pharmacy dispensing practices of mifepristone/misoprostol in the absence of a prescription.
Study Design: Using two predetermined client profiles-one of an unmarried woman and one of her male partner-we visited community pharmacies in different neighborhoods.
Discharge Opioid Prescription and Consumption Following Surgery: The POPCORN Observational Study.
Can J Hosp Pharm
September 2024
, PharmD, MSc, is with the Faculty of Pharmacy, Université de Montréal; and the Department of Pharmacy and Lady Davis Institute, Jewish General Hospital, Montréal, Quebec. At the time this study was conducted, Kenzi Wassil Mohktari, Anna Wong, Michelle Nguyen, Arianne Giard, Brian Ly, were students in the Faculty of Pharmacy, Université de Montréal. They have now graduated and are working there as clinicians.
Background: Few studies have evaluated opioid consumption after various inpatient surgical procedures.
Objectives: To describe opioid prescription patterns and to characterize patient-reported use of opioids after surgery.
Methods: This single-centre prospective observational study was conducted between February and October 2021 at the Jewish General Hospital in Montréal, Quebec.
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