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JAMA Dermatol
March 2024
Sinclair Dermatology, East Melbourne, Victoria, Australia.
Importance: Current measures of alopecia areata (AA) severity, such as the Severity of Alopecia Tool score, do not adequately capture overall disease impact.
Objective: To explore factors associated with AA severity beyond scalp hair loss, and to support the development of the Alopecia Areata Severity and Morbidity Index (ASAMI).
Evidence Review: A total of 74 hair and scalp disorder specialists from multiple continents were invited to participate in an eDelphi project consisting of 3 survey rounds.
Background: Around 500 000 people worldwide develop rifampicin-resistant tuberculosis each year. The proportion of successful treatment outcomes remains low and new treatments are needed. Following an interim analysis, we report the final safety and efficacy outcomes of the TB-PRACTECAL trial, evaluating the safety and efficacy of oral regimens for the treatment of rifampicin-resistant tuberculosis.
View Article and Find Full Text PDFSud Med Ekspert
February 2022
On October 21-22, 2021, the All-Russian Scientific-Practical Conference with international participation "Milestones in the History of Russian Center of Forensic Medicine was held in full-time distance format (with online broadcasting). To the 90th anniversary of its establishment".
View Article and Find Full Text PDFMedicine (Baltimore)
May 2020
Department of Hematology, Inner Mongolia Baogang Hospital (The Third Affiliated Hospital of Inner Mongolia Medical University), No. 20 Shaoxian Road, Kundulun District, Baotou, Inner Mongolia Autonomous Region, 014010, China.
Background: To systematic review the efficacy and safety of 6-thioguanine (6-TG) in the substitute of 6-mercaptopurine (6-MP) in the treatment for patients with childhood acute lymphoblastic leukemia (ALL) in the maintenance phase, and to explore its clinical application value. It provides theoretical guidance for the maintenance treatment of ALL in children from the perspective of evidence-based medicine.
Methods: By means of computer retrieval, Chinese databases were searched: Chinese Biomedical Database (CBM), China national knowledge internet (CNKI), Chongqing Weipu Database (VIP), and Wanfang Database; Foreign databases: PubMed, The Cochrane Library, Embase, and Web of Science were applied to find out randomized controlled trial (RCT) for 6-TG in childhood acute lymphoblastic leukemia.
Zh Nevrol Psikhiatr Im S S Korsakova
January 2019
Mental Health Research Center, Moscow, Russia.
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