AI Article Synopsis
- Nucleic acids, like DNA, play a crucial role in gene expression and can influence cell death.
- Left-handed Z-DNA might act as a transcriptional enhancer, potentially affected by processes that lead to cell differentiation.
- The nicking and denaturation of Z-DNA could trigger and promote terminal differentiation in certain tissues.
Article Abstract
Nucleic acids control the expression of genes, and different conformations of DNA structure may regulate cell death. Left-handed Z-DNA, which is speculated to function as a transcriptional enhancer, may be directly influenced by the destructive effects of terminal differentiation. The nicking-denaturation of double-stranded Z-DNA could possibly initiate and enhance terminal differentiation within specific tissues.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1006/cbir.1998.0327 | DOI Listing |
Publication Analysis
Top Keywords
terminal differentiation
12
left-handed z-dna
8
differentiation left-handed
4
z-dna review
4
review nucleic
4
nucleic acids
4
acids control
4
control expression
4
expression genes
4
genes conformations
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!