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Global prevalence of lagomorpha coccidiosis from 1951 to 2024: A systematic review and meta-analysis.
Res Vet Sci
February 2025
School of Public Health, Lanzhou University, Lanzhou 730000, Gansu Province, China. Electronic address:
The global prevalence of coccidia infection in lagomorphs and potential risk factors were investigated through a meta-analysis of 149 studies published between 1951 and 2024. The pooled prevalence of Eimeriidae, Sarcocystidae and Cryptosporidiidae was found to be 66.0 %, 8.
View Article and Find Full Text PDFBackground: Diarrhoeal diseases claim more than 1 million lives annually and are a leading cause of death in children younger than 5 years. Comprehensive global estimates of the diarrhoeal disease burden for specific age groups of children younger than 5 years are scarce, and the burden in children older than 5 years and in adults is also understudied. We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2021 to assess the burden of, and trends in, diarrhoeal diseases overall and attributable to 13 pathogens, as well as the contributions of associated risk factors, in children and adults in 204 countries and territories from 1990 to 2021.
View Article and Find Full Text PDFSelective targeting of phosphodiesterases to develop potent antiparasitic drugs.
Trends Parasitol
December 2024
Department of Pathobiology, College of Veterinary Medicine, University of Illinois Urbana-Champaign, Urbana, IL, USA. Electronic address:
Regulation of intracellular cyclic nucleotides to avoid homeostatic imbalances is achieved through catabolic activity of phosphodiesterases (PDEs). Recently, Ajiboye et al. reported validation of Cryptosporidium PDE1 (CpPDE1) as a viable drug target and identified optimized pyrazolopyrimidines with selective activity against CpPDE1 over human PDEs and with potent anticryptosporidial efficacy.
View Article and Find Full Text PDFSimultaneous biomass concentration and subsequent quantitation of multiple infectious disease agents and antimicrobial resistance genes from community wastewater.
Environ Int
September 2024
Finnish Institute for Health and Welfare, Expert Microbiology Unit, Neulaniementie 4, Kuopio FI-70701, Finland; University of Helsinki, Faculty of Veterinary Medicine, Department of Food Hygiene and Environmental Health, Agnes Sjöbergin katu 2, Helsinki FI-00014, Finland. Electronic address:
Wastewater-based surveillance (WBS) of infectious disease agents is increasingly seen as a reliable source of population health data. To date, wastewater-based surveillance efforts have largely focused on individual pathogens. However, given that wastewater contains a broad range of pathogens circulating in the population, a more comprehensive approach could enhance its usability.
View Article and Find Full Text PDFMarked increase in cryptosporidiosis cases, Spain, 2023.
Euro Surveill
July 2024
The members of the working group for the National Surveillance Network are listed under Collaborators.
BackgroundBy mid-September 2023, several event notifications related to cryptosporidiosis had been identified from different regions in Spain. Therefore, a request for urgent notification of cryptosporidiosis cases to the National Surveillance Network was launched.AimWe aimed at assessing the extent of the increase in cases, the epidemiological characteristics and the transmission modes and compared to previous years.
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