The purpose of this study was to determine the prevalence of oral lesions in a private dental practice, which treats a broad spectrum of patients from both urban and rural areas. All oral lesions were documented over a 30 month period in a research programme, which formed part of the normal patient treatment plan. The lesions were analysed according to the prevalence of the lesions, race, age and gender distribution, and the ratio of lesions diagnosed by the practitioner compared with those presented for treatment by the patients. A total of 8418 patients were examined and 151 pathological lesions were diagnosed, representing 46 different conditions. The commonest conditions were fluorosis (11 per cent of lesions) and geographic tongue (11 per cent of lesions seen). Twenty conditions (47.8 per cent) were seen only once. The male:female ratio was 1.17:1. A total of 74 per cent of the lesions were seen in patients between the 2nd and the 5th decades and 25 per cent in the 4th decade. Patients seeking treatment suffered from conditions such as fluorosis causing aesthetic problems. On the other hand premalignant lesions such as leukoplakia and life threatening diseases were usually detected by the dentist, which stresses the importance of a thorough clinical examination of all patients. Fluorosis documented in 17 patients in this study, led to analysis of drinking water in the Dennilton area, which was found to contain toxic levels of fluoride.
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Objective: Transrectal (TR) prostate biopsy is being increasingly abandoned in favour of a transperineal (TP) approach as well as a targeted biopsy only of the index lesion(s). It remains underreported how these changes could impact concordance at final pathology. We aimed to evaluate the impact of transitioning from standard transrectal (sTR) to cognitive targeted transperineal (cog-tTP) biopsy on final pathology including concordance and upgrading.
View Article and Find Full Text PDFAustralas J Dermatol
January 2025
The Frazer Institute, The University of Queensland, Brisbane, Queensland, Australia.
Background: Recent Australian trends indicate that shave biopsies for diagnosing lesions suspicious of melanoma are increasing, yet reasons for this remain relatively unknown. We sought to understand which factors influence Australian clinicians' use of shave biopsy for managing thin lesions suspicious of melanoma in sites of low cosmetic sensitivity.
Methods: We used a convergent, exploratory mixed-methods design, with a cross-sectional online survey (n = 59) and semi-structured qualitative interviews (n = 15).
Liver Int
February 2025
Sorbonne Université, Service Médecine Interne, Centre de référence des maladies autoinflammatoires et des amyloses (CEREMAIA), Assistance Publique des hôpitaux de Paris, Hôpital Tenon, Paris, France.
Background: Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory disease, associated with MEFV mutations. FMF patients can experience liver involvement, potentially leading to cirrhosis.
Objectives: This study aimed to evaluate liver involvement in FMF patients at a French tertiary centre for adult FMF.
J Cent Nerv Syst Dis
January 2025
CRCSEP, Université Nice Cote d'Azur, Nice, France.
Multiple sclerosis (MS) falls within the spectrum of central nervous system (CNS) demyelinating diseases that may lead to permanent neurological disability. Fundamental to the diagnosis and clinical surveillance is magnetic resonance imaging (MRI) that allows for the identification of T2-hyperintensities associated with autoimmune injury that demonstrate distinct spatial distribution patterns. Here, we describe the clinical experience of a 31-year-old, right-handed, White man seen in consultation at The University of Texas Southwestern Medical Center in Dallas, Texas, following complaints of headaches that began after head trauma related to military service.
View Article and Find Full Text PDFKnee Surg Sports Traumatol Arthrosc
January 2025
Hospital Parc Taulí, Imove Traumatología, Barcelona, Spain.
Purpose: Studies evaluating the long-term survival rate, patient satisfaction, and conversion to total hip arthroplasty (THA) are limited. The aim of this study was to evaluate satisfaction and hip survival at a minimum 10-year follow-up in patients following hip arthroscopy for femoroacetabular impingement syndrome (FAIS).
Methods: A total of 164 patients underwent hip arthroscopy for FAIS between 2007 and 2012; of these, 76 (49 men and 27 women; mean age, 40.
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