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Article Synopsis
  • The study discusses a case of a 21-year-old woman with rare, grouped lesions known as acquired agminated nevi located in her axillae.
  • Using a picosecond 532 nm Nd:YAG laser, significant cosmetic improvement was achieved after multiple treatments, outperforming other laser types.
  • The research highlights the uniqueness of the case due to the bilateral occurrence of the nevi and emphasizes the importance of monitoring post-treatment since potential risks like atypia and melanoma can arise.
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Agminated blue nevi: a case series and updated dermoscopic review.

Postepy Dermatol Alergol

December 2022

Department of Dermatology, Venereology and Allergology, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland.

Blue nevi, usually presenting as solitary, bluish, asymptomatic macules or nodules, are formed by collections of dermal melanocytes that failed to complete their migration from the neural crest to the dermo-epidermal junction. The term "agminated blue nevi" refers to multiple lesions grouped, linear, or arranged in a blashkoid distribution. It is a relatively rare phenomenon with less than 35 cases reported in the literature, but only 14 cases with dermoscopic features.

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Lymphomatoid papulosis (LYP), the most common primary cutaneous CD30-positive lymphoproliferative disorder, is heralded by multiple papular and nodular lesions at anatomically discontiguous cutaneous sites. The histologic patterns are protean. An uncommon form of LYP is one that is anatomically confined.

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A 59-year-old woman presented with a persistent eruption manifested as multiple agminated miliary facial papules. Histopathological examination showed prominent nodular dermal lymphoid infiltrates with hyperplastic follicles that were initially interpreted as B-cell reactive lymphoid hyperplasia. Several years later, an additional biopsy showed a dense perifollicular infiltrate with reactive primary and secondary follicles.

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