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The Effect of a Zeolite Addition to Modified Bitumen on the Properties of Stone Matrix Asphalt Lärmarmer Mixtures Produced as Warm Mix Asphalt.
Materials (Basel)
November 2024
Faculty of Civil and Environmental Engineering and Architecture, Rzeszow University of Technology, Powstancow Warszawy 12 Avenue, 35-959 Rzeszow, Poland.
This paper presents the properties of an SMA LA (stone matrix asphalt Lärmarmer) mixture based on the polymer-modified binder PMB 45/80-55, formed by the addition of zeolites (synthetic zeolite type Na-P1 and natural zeolite-clinoptilolite). The compositions of the SMA 11, SMA 8 LA and SMA 11 LA mixtures based on modified bitumen with PMB 45/80-55 (reference mixture) or PMB 45/80-55 with Na-P1 or clinoptilolite were determined. Their resistance to permanent deformation, water sensitivity, water permeability and susceptibility to changes in texture and skid resistance during the period of use were verified.
View Article and Find Full Text PDFSynthesis and Identification of Heterobivalent Anticancer Compounds Containing Urea and 5-Arylidene-2-Thiohydantoin Motifs.
ChemistrySelect
March 2024
Department of Drug Discovery & Biomedical Sciences, University of South Carolina, 517 Sumter St., CLS 617, Columbia, SC 29208.
Urea and thiohydantoin are among the important privileged structures for drug discovery. We have developed a synthetic approach to the high-throughput synthesis of the heterobivalent compounds containing both urea and 5-arylidene-2-thiohydantoin functional groups. This synthetic methodology was applied to the synthesis of a mixture-based library containing a total of 5280 compounds in a positional scanning format.
View Article and Find Full Text PDFIdentification of B Cell and T Cell Epitopes Using Synthetic Peptide Combinatorial Libraries.
Curr Protoc
March 2022
Center for Translational Science, Florida International University, Port St. Lucie, Florida.
This article presents a combinatorial library method that consists of the synthesis and screening of mixture-based synthetic combinatorial libraries of peptide molecules to identify B and T cell epitopes. The protocols employ peptide libraries to identify peptides recognized by MAbs and T cells. The first protocol uses a positional scanning peptide library made up of hexapeptides to identify antigenic determinants recognized by MAbs.
View Article and Find Full Text PDFUse of Complementary Natural Feed for Gastrointestinal Nematodes Control in Sheep: Effectiveness and Benefits for Animals.
Animals (Basel)
November 2019
Department of Health Sciences, University of Catanzaro "Magna Græcia", CISVetSUA, 88100 Catanzaro, Italy.
The treatments of gastrointestinal nematodes (GIN) infection in sheep is almost exclusively based on the use of synthetic drugs. In some European regions the intensive use of antiparasitic drugs is leading to widespread development of anthelmintic resistance (AR). Currently in southern Italy AR is rare, but a constant monitoring of anthelmintic efficacy and the use of effective alternative therapies is strongly recommended.
View Article and Find Full Text PDFVariational Bayesian Learning of Generalized Dirichlet-Based Hidden Markov Models Applied to Unusual Events Detection.
IEEE Trans Neural Netw Learn Syst
April 2019
Learning a hidden Markov model (HMM) is typically based on the computation of a likelihood which is intractable due to a summation over all possible combinations of states and mixture components. This estimation is often tackled by a maximization strategy, which is known as the Baum-Welch algorithm. However, some drawbacks of this approach have led to the consideration of Bayesian methods that add a prior over the parameters in order to work with the posterior probability and the marginal likelihood.
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