Aim: in recent years there have been remarkable advances in the treatment of rectal cancer, stimulated by a general tendency towards conservative treatment, and aided by the development of diagnostic tools that allow the surgeon to select the most suitable tumors for treatment. In some cases, conservative local excision by transanal endoscopic microsurgery (TEM) may be appropriate. We analyzed the value of transrectal endosonography for the preoperative staging of rectal cancer previous to TEM.
Methods: data were collected prospectively from a consecutive series of patients with rectal cancer who underwent TEM between January 1994 and December 1997.
Results: the accuracy of rectal endosonography in predicting rectal wall invasion was 72.7%. 18.2% of the tumors were overstaged and 9. 1% were understaged.
Conclusion: transrectal endosonography is a useful technique for the selection of patients for TEM but is amenable to further improvement.
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Mol Cancer
January 2025
i3S - Instituto de Investigação e Inovação em Saúde, Universidade Do Porto, Rua Alfredo Allen 208, Porto, 4200‑135, Portugal.
Rectal cancer accounts for over 35% of the worldwide colorectal cancer burden representing a distinctive subset of cancers from those arising in the colon. Colorectal cancers exhibit a continuum of traits that differ with their location in the large intestine. Due to anatomical and molecular differences, rectal cancer is treated differently from colon cancer, with neoadjuvant chemoradiotherapy playing a pivotal role in the control of the locally advanced disease.
View Article and Find Full Text PDFSci Data
January 2025
The Griffin Institute, Northwick Park and St Mark's Hospital, Watford Road, London, HA13UJ, UK.
Minimally invasive surgery is complex and prone to variation not routinely objectively measured. We established an association between skills and patient outcomes. The evolving application of artificial intelligence techniques could assist intraoperative analysis.
View Article and Find Full Text PDFPLoS One
January 2025
Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, Jiangsu, PR. China.
Objectives: The aim of this study was to develop and validate a nomogram model that predicts the risk of bone metastasis (BM) in a prostate cancer (PCa) population.
Methods: We retrospectively collected and analyzed the clinical data of patients with pathologic diagnosis of PCa from January 1, 2013 to December 31, 2022 in two hospitals in Yangzhou, China. Patients from the Affiliated Hospital of Yangzhou University were divided into a training set and patients from the Affiliated Clinical College of Traditional Chinese Medicine of Yangzhou University were divided into a validation set.
Sex Health
January 2025
Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.
Background Human papillomavirus (HPV)-associated cancers are a global concern, particularly for sexual minority men (SMM). Understanding awareness and the determinants of these beliefs is crucial for developing educational programs to reduce HPV-associated cancers. This study explored awareness and determinants of beliefs about HPV's carcinogenicity among SMM living with and without HIV in Nigeria.
View Article and Find Full Text PDFInt Urol Nephrol
January 2025
Department of Urology, Faculty of Medicine, Cairo University, Cairo, Egypt.
Objective: To evaluate the outcomes and efficacy of robot-assisted radical prostatectomy (RARP) using the Versius robotic surgical system, aiming to provide comprehensive data on perioperative outcomes, postoperative recovery, and complications.
Patient And Methods: All cases of RARP using the CMR Versius platform performed at Cairo University Hospital over a two-year period were enrolled in this study. All patients had pathologically confirmed prostate cancer in both localized and locally advanced stages.
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