AI Article Synopsis
- The study investigated the impact of alternating imipenem and cefoperazone/sulbactam on antibiotic resistance in an ICU setting.
- Between April 1993 and April 1994, patients were treated without alternative therapy, while the following two years involved daily follow-ups and a new therapy protocol.
- The research found that the sensitivity rates for imipenem, ciprofloxacin, and aminoglycosides improved with the implementation of this protocol.
Article Abstract
In this study, the effects of alternate use of imipenem and cefoperazone/sulbactam(CFP/Sul) on antibiotic resistance in the intensive care unit (ICU) were investigated. Between 1 April 1993 and 1 April 1994, the infectious diseases consultant saw patients when required and there was no alternative therapy for antibiotics. For the following 2 years, the same consultant followed up each patient from admission to discharge by daily visits to the ICU and an alternative therapy protocol was initiated. The most common microorganisms were found to be Acinetobacter baumannii and Staphylococcus aureus, followed by Pseudomonas aeruginosa and Klebsiella pneumoniae, respectively, in the two periods. This study demonstrated that sensitivity rates of imipenem, ciprofloxacin and aminoglycosides were improved as a result of this protocol.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s001340050998 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Effectiveness and safety of talimogene laherparepvec and granulocyte-macrophage colony-stimulating factor for metastatic melanoma: a systematic review and network meta-analysis of randomized controlled trials.
Melanoma Res
February 2025
Department of Public Health, College of Medicine, Taipei Medical University.
Melanoma is an aggressive tumor that is challenging to treat. Talimogene laherparepvec (T-VEC), the first oncolytic virus treatment approved by the US Food and Drug Administration to treat unresectable melanoma, was recently used in recurrent tumors after initial surgery. Our network meta-analysis aimed to compare T-VEC treatment of metastatic melanoma with treatment of granulocyte-macrophage colony-stimulating factor (GM-CSF) and control group.
View Article and Find Full Text PDFKinetic Oscillation Stimulation for the Preventive Treatment of Chronic Migraine: A Randomized, Double-Blind, Sham-Controlled Trial.
Neurology
February 2025
Department of Systems Neuroscience, University Medical Center Hamburg-Eppendorf, Germany.
Background And Objectives: The Chordate System administers kinetic oscillation stimulation (K.O.S) into the nasal cavity thereby potentially modulating the activity of trigemino-autonomic reflex.
View Article and Find Full Text PDF8-Hydroxyquinoline derivative as a promising antifungal agent to combat ocular fungal infections.
J Med Microbiol
January 2025
Programa de Ps-Graduao em Cincias Farmacuticas, Faculdade de Farmcia, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Ocular fungal infections are pathologies of slow progression, occurring mainly in the cornea, but can also affect the entire structure of the eyeball. The main aetiological agents are species of the genera and . Both diagnosis and treatment require speed and effectiveness.
View Article and Find Full Text PDFCase: We present a 79-year-old woman with a complex elbow fracture including a comminuted proximal ulna fracture, coronoid process fracture, and comminuted radial head fracture treated with primary total elbow arthroplasty (TEA). The patient completed an early therapy protocol and had complete healing. At 15 months postoperatively, she had full pronosupination and elbow arc of motion from 10 to 135° with no reported pain.
View Article and Find Full Text PDFCellular therapy for the peripheral arterial disease treatment: Protocol for a systematic review and meta-analysis.
PLoS One
January 2025
Department of Nursing and Podiatry, University of Malaga, Malaga, Spain.
Cellular therapy is a promising treatment option for Peripheral Arterial Disease (PAD). Different cell types can be used to regenerate and repair tissues affected by PAD. Many studies have proposed the use of stem cells, such as mesenchymal stem cells, or even mononuclear cells isolated from peripheral blood or bone marrow, to treat PAD.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!