AI Article Synopsis

  • Chronic experiments were done on rats and rabbits to study carbidine's effect on conditioned defense reflexes related to the brain's reticular formation.
  • Carbidine was found to prevent the depression of these reflexes when the mesencephalic part of the reticular formation was stimulated, indicating its depressive influence on these brain structures.
  • Additional experiments with rabbits confirmed these findings by showing changes in biocurrents during stimulation of the mesencephalic reticular formation.

Article Abstract

Chronic experiments were conducted on rats and rabbits; a study was made of the effect of carbidine on the conditioned defence reflexes in stimulation of the mesencephalic part of the reticular formation. Carbidine prevented the depression of the conditioned defence reflexes caused by stimulation of the mesencephalic portion of the reticular formation. This pointed to its depressive influence on the mentioned structures, and was confirmed by experiments on rabbits in recording changes in biocurrents under conditions of stimulation of the mesencephalic reticular formation.

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