Aversectin C was evaluated for mutagenic activity in the Ames test with Salmonella typhimurium TA 97, TA 98 and TA 100, in the dominant lethal assay on uninbred albino rats in a dose of 2.25 mg/kg body weight (1/40 of the LD50) and in the metaphase test on F1CBAxC57BI/6 mice in a dose of 8.2 mg/kg body weight (1/5 of the LD50). The agent showed no mutagenic activity in any of the tests. The anaphase test on F1CBAxC57BI/6 mice revealed no antimitotic activity of aversectin C.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
mutagenic activity
12
activity aversectin
8
mg/kg body
8
body weight
8
test f1cbaxc57bi/6
8
f1cbaxc57bi/6 mice
8
[assessment mutagenic
4
activity
4
aversectin aversectin
4
aversectin evaluated
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!