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Optimization and Standardization of the Extraction Method of Del. Seeds (Zygophyllaceae) Used in the Formulation of an Antiparasitic Phytomedicine.
Pharmaceuticals (Basel)
December 2024
Laboratoire de Recherche-Développement de Phytomédicaments et Médicaments (LR-D/PM), Institut de Recherche en Sciences de la Santé (IRSS), Centre National de la Recherche Scientifique et Technologique (CNRST), Ouagadougou 03 BP 7047, Burkina Faso.
Del. (Zygophyllaceae) is widely used in traditional medicine, both human and veterinary, throughout Africa for its many properties, including antiparasitic properties. This experimental study aims to optimize the extraction conditions of the seeds of Del.
View Article and Find Full Text PDFSynthesis, in vivo evaluation, and in silico molecular docking of benzo[h]quinoline derivatives as potential Culex pipiens L. larvicides.
Bioorg Chem
December 2024
Chemistry Department, Faculty of Science, Ain Shams University, Cairo 11566, Egypt. Electronic address:
A new series of benzo[h]quinoline-containing heterocycles was synthesized via reactions of benzo[h]quinolinyl-2(3H)-furanone with some nitrogen bidentate nucleophiles, leading to the formation of pyridazinone, pyrrolinone, benzimidazole, and benzoxazinone derivatives. The synthesized compounds were evaluated for their insecticidal activity against Culex pipiens L. larvae.
View Article and Find Full Text PDFPhyto-pharmacological wonders of genus : Ethnopharmacological insights and phytochemical treasures from natural products.
Saudi Pharm J
December 2024
Central Laboratory of The Lishui Hospital of Wenzhou Medical University, The First Affiliated Hospital of Lishui University, Lishui People's Hospital, Lishui, Zhejiang, 323000, China.
Natural products have perennially served as a cornerstone for the genesis of novel medicinal compounds. Most clinical therapeutics originate from ancestral herbal remedies and their formulations. Scholars and practitioners have always aimed to extract better remedies to treat various ailments.
View Article and Find Full Text PDFControl of dengue larvae of Aedes aegypti and Aedes albopictus using the larvicidal bioactive compounds in different plant extracts and plant extract-mediated nanoparticles.
Trop Med Health
December 2024
Department of Biological Sciences, Macquarie University, Sydney, NSW, Australia.
Article Synopsis
- Dengue is a serious viral disease spread by Aedes mosquitoes, and effective control of mosquito populations is crucial for prevention.
- Synthetic insecticides are limited due to health and environmental risks, leading to a preference for eco-friendly, biologically synthesized alternatives.
- Plant-derived bioassays and nanoparticles, particularly those made from plants, show promising larvicidal effects against Aedes mosquito larvae, offering a safer and more sustainable control method.
In Vitro Bioassay and In silico Pharmacokinetic Characteristics of Xanthium strumarium Plant Extract as Possible Acaricidal Agent.
Curr Pharm Des
December 2024
Department of Pathology, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chiayi 600, Taiwan.
Background: Effective management strategies against tick infestations are necessary because tickborne diseases represent serious hazards to the health of humans and animals worldwide. The aim of this study was to examine the larvicidal and ovicidal properties of Xanthium strumarium extract against a notorious tick species, Rhipicephalus microplus.
Methodology: The maceration method was used to prepare the ethanolic extract of X.
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