Role of the sodium-hydrogen exchanger in ischemia-reperfusion injury in diabetes.

J Thromb Thrombolysis

Cell Biology Laboratory, Division of Stroke and Vascular Disease, St. Boniface General Hospital Research Centre, Winnipeg, Manitoba, Canada.

Published: July 1999

Ischemic heart disease is a significant problem in the diabetic population. Animal models of diabetes show a paradoxical resistance to ischemic challenge. The present treatise will discuss the mechanics involved and the central role that Na+-H+ exchanger plays in this response to ischemic-reperfusion injury.

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Source
http://dx.doi.org/10.1023/a:1008994631084DOI Listing

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