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Atherogenic Dyslipidemia Is Critically Related to Aortic Complicated Lesions in Cryptogenic Stroke.
J Atheroscler Thromb
December 2024
Department of Neurology, Juntendo University Urayasu Hospital.
Aims: Atherogenic dyslipidemia (AD) is regarded as a residual risk of cardiovascular diseases characterized by low high-density lipoprotein cholesterol (HDL-C) and high triglyceride (TG) levels and related to the intracranial stenosis of atheromatous thrombotic brain infarction (ATBI). Further, atherosclerosis is possibly related to another stroke subtype, including cryptogenic stroke (CS). In particular, an aortic complicated lesion (ACL) is a notable embolic source of CS, since recurrence of aortogenic brain embolism is not rare.
View Article and Find Full Text PDFSmall-vessel vasculitis associated with cholesterol embolism: a case report.
BMC Rheumatol
December 2024
Department of General Internal Medicine, Kobe City Medical Center General Hospital, 2-1-1 Minami-Machi, Minatojima, Chuo-Ku, Kobe, Hyogo, 650-0047, Japan.
Background: Cholesterol embolism causes various organ dysfunctions, including skin, kidney, and gastrointestinal tract dysfunction, as well as immunological abnormalities, such as hypocomplementemia and eosinophilia. However, only a few cases of vasculitis accompanied by cholesterol embolism have been reported.
Case Presentation: We present the case of an 82-year-old man with cholesterol embolism who also developed small-vessel vasculitis of the skin and muscles.
Cholesterol Crystal Embolism Following Mechanical Thrombectomy for Acute Ischemic Stroke.
Cureus
October 2024
Department of Neurosurgery, International University of Health and Welfare Narita Hospital, Narita, JPN.
Cholesterol crystal embolism (CCE) is a rare but serious complication of atherosclerotic plaque rupture, often occurring after endovascular interventions. We report the case of a 73-year-old man who developed CCE following mechanical thrombectomy (MT) for an acute ischemic stroke (AIS) due to left internal carotid artery occlusion. The patient, with a history of hypertension and hyperlipidemia, underwent successful MT with complete recanalization.
View Article and Find Full Text PDFAn 80-year-old man presented to our hospital with worsening renal function and ambulation difficulties due to lower extremity symptoms that included livedo reticularis, gangrene, cyanosis, and ulcers in his legs. The patient was diagnosed with a cholesterol crystal embolism. Treatment with prednisolone and rosuvastatin was initiated; however, no improvements were observed in the patient's cutaneous symptoms or renal function.
View Article and Find Full Text PDFBlue toe syndrome - systemic cholesterol crystal embolism secondary to cardiovascular procedures: a forensic autopsy report of two cases.
Forensic Sci Med Pathol
November 2024
Department of Legal Medicine, Kyorin University School of Medicine, 6- 20-2 Shinkawa, Mitaka-shi, Tokyo, 181-8611, Japan.
Blue toe syndrome, also referred to as cholesterol crystal embolism is characterized by the distal embolization of cholesterol crystals originating from ruptured atherosclerotic plaques. This condition commonly arises in the context of cardiovascular procedures. Emboli from the thoracoabdominal aorta primarily affect the downstream extremities and intra-abdominal viscera, often resulting in fatal atheroembolic renal failure.
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