Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/(SICI)1098-1004(1999)14:3<272::AID-HUMU21>3.0.CO;2-V | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Automated Neural Architecture Search for Cardiac Amyloidosis Classification from [18F]-Florbetaben PET Images.
J Imaging Inform Med
October 2024
Bioengineering Unit, Fondazione Toscana G Monasterio, Via Giuseppe Moruzzi, 56124, Pisa, Italy.
Article Synopsis
- - Medical image classification using convolutional neural networks (CNNs) usually needs a lot of manual adjustments, but neural architecture search (NAS) can automate this process, making it more efficient.
- - This study focuses on classifying different sub-types of cardiac amyloidosis using NAS on [18F]-Florbetaben PET cardiac images, with a significant dataset augmentation from 597 to 4048 images, resulting in 5000 evaluated architectures.
- - The best-performing network, named NAS-Net, achieved 76.95% overall accuracy and showed impressive sensitivity and specificity rates for the AL and ATTR-CA subjects, confirming that NAS can rival traditional methods while using fewer parameters.
Maribavir treatment for resistant cytomegalovirus disseminated disease in kidney transplant recipients: A case-based scoping review of real life data in literature.
Transplant Rev (Orlando)
December 2024
Department of Medical Sciences, Infectious Diseases, University of Turin, 10126 Turin, Italy.
The treatment of refractory CMV is often associated with high toxicity. Maribavir (MBV) is a novel oral antiviral, known for its favourable safety profile in fragile patients. We describe a case of CMV disease with end organ damage following kidney transplantation at high risk, for recipient-donor serological mismatch.
View Article and Find Full Text PDFPEMPS: a phylogenetic software tool to model the evolution of metabolic pathways.
BMC Bioinformatics
July 2024
Department of Biology and Center for Computational Genetics and Genomics, Temple University, Philadelphia, PA, 19122, USA.
Background: Metabolic pathways support the enzyme flux that converts input chemicals into energy and cellular building blocks. With a constant rate of input, steady-state flux is achieved when metabolite concentrations and reaction rates remain constant over time. Individual genes undergo mutation, while selection acts on higher level functions of the pathway, such as steady-state flux where applicable.
View Article and Find Full Text PDFNonsyndromic Craniosynostosis Correlation Between Ethnicity, Race, and Pattern of Affected Suture Type: Meta-Analysis.
J Craniofac Surg
July 2024
Division of Plastic and Reconstructive Surgery, Icahn School of Medicine at Mount Sinai, New York, NY.
Background: Previous studies have sought to analyze risk factors associated with craniosynostosis and while syndromic craniosynostosis is often linked to genetic mutations, the factors impacting nonsyndromic cases are less investigated. The aim of current meta-analysis is to evaluate the relationship between ethnicity and suture type in nonsyndromic craniosynostosis patients.
Methods: The search term "craniosynostosis [Title/Abstract] AND (race [Title/Abstract] OR ethnicity [Title/Abstract])) NOT (syndrome [Title/Abstract])" was used to search the PubMed, Cochrane, and MEDLINE databases.
Aberrant RNA polymerase initiation and processivity on the genome of a herpes simplex virus 1 mutant lacking ICP27.
J Virol
June 2024
Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Within the first 15 minutes of infection, herpes simplex virus 1 immediate early proteins repurpose cellular RNA polymerase (Pol II) for viral transcription. An important role of the viral-infected cell protein 27 (ICP27) is to facilitate viral pre-mRNA processing and export viral mRNA to the cytoplasm. Here, we use precision nuclear run-on followed by deep sequencing (PRO-seq) to characterize transcription of a viral ICP27 null mutant.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!