As many as 44 patients with stage IIIB and IV carcinoma of the lung (n = 27 and 17 respectively) were studied for clinical and laboratory manifestations of endogenous intoxication syndrome during the administration of CAPF chemotherapy treatments. The use for detoxicating purposes of siliceous enterosorbents and plasmapheresis both alone and combined resulted in alleviation of gastrointestinal and hematological complications and permitted improving the quality of the patients' lives.

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