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WF14861, a new cathepsins B and L inhibitor produced by Colletotrichum sp. I. Taxonomy, production, purification and structure elucidation. | LitMetric
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WF14861, a new cathepsins B and L inhibitor produced by Colletotrichum sp. I. Taxonomy, production, purification and structure elucidation.

T Otsuka Y Muramatsu T Higaki T Nakanishi S Takase H Hatanaka M Okamoto M Hino S Hashimoto

J Antibiot (Tokyo)

Exploratory Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., Tsukuba, Ibaraki, Japan.

Published: June 1999

WF14861, a novel cathepsins B and L inhibitor, was obtained from the culture mycelium of a fungus strain Colletotrichum sp. No. 14861. Spectroscopic analysis showed that WF14861 consisted of trans-epoxysuccinic acid, L-tyrosine and spermidine, WF14861 inhibited cathepsins B and L selectively.

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 Source
http://dx.doi.org/10.7164/antibiotics.52.536DOI Listing

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