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High prevalence and incidence of systemic sclerosis in Reunion Island, a French multi-ethnical and tropical territory.
Semin Arthritis Rheum
February 2025
Service de médecine interne et dermatologie, Hôpital Felix Guyon, CHU de la Réunion, 1 allée des Topazes 97400, Saint-Denis, France.
Article Synopsis
- The study aimed to determine the prevalence and incidence of systemic sclerosis (SSc) on Reunion Island, focusing on its multi-ethnic population and possible environmental and genetic influences.
- Researchers reviewed SSc cases from 2005 to 2021, classifying patients into subsets based on skin conditions and assessing their ethnicity and skin type.
- The findings showed a prevalence of 30.9 cases per 100,000 in 2021 and an annual incidence of 2.13 per 100,000, with results indicating that darker skin types often had pulmonary issues, while lighter skin types experienced more severe gastrointestinal problems.
Does therapy with immunosuppressive drugs improve gastrointestinal symptoms in patients with systemic sclerosis?
RMD Open
July 2024
Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland
Article Synopsis
- The study focused on the lack of effective treatments for gastrointestinal (GI) symptoms in patients with systemic sclerosis (SSc) and examined the impact of immunosuppressive therapy on these symptoms.
- Researchers analyzed 209 SSc patients and found that those undergoing immunosuppressive therapy experienced less severe GI symptoms, as measured by a specialized scoring tool, compared to those not receiving this treatment.
- The findings suggest immunosuppressants may improve GI manifestations in SSc, but further confirmation through randomized clinical trials is needed.
Symptom experience of limited cutaneous systemic sclerosis from the Patients' perspective: A qualitative study.
Semin Arthritis Rheum
February 2022
Michigan Scleroderma Program, University of Michigan, Ann Arbor, MI, USA; Division of Rheumatology, University of Michigan, Ann Arbor, Michigan, USA.
Objectives: Limited cutaneous systemic sclerosis (lcSSc) is the largest subgroup of people with SSc, but little is known about symptom experience from the patients' perspective. This study aimed to comprehensively identify domains and symptoms reported as bothersome by patients with lcSSc and to analyze themes and sub-themes capturing symptom experience in this population.
Methods: Focus groups of patients with lcSSc were conducted using a structured guide.
Oesophageal motor disorders and oesophageal endoscopic involvement in patients with systemic sclerosis: a systematic association?
Scand J Gastroenterol
May 2021
Internal Medicine Department, CHU La Timone, Assistance Publique Hôpitaux de Marseille (AP-HM), Aix-Marseille University, Marseille, France.
Introduction: Although oesophageal motor disorders (OMDs) are frequent in systemic sclerosis (SSc), the frequency of associated endoscopic lesions is unknown. We aimed at assessing the presence of endoscopic lesions in SSc patients with OMD. The secondary objective was to identify the clinical and serological profile of such patients.
View Article and Find Full Text PDF[Monocentric study on pharmaceuticals taken by patients to treat systemic sclerosis].
Rev Med Interne
February 2021
Service de médecine interne, centre hospitalo-universitaire, Hôtel-Dieu, 1, place Alexis-Ricordeau, 44000 Nantes, France.
Introduction: Pharmaceutical prescription in systemic sclerosis is guided by national and international recommendations. This study's primary objective was to describe and analyze these prescriptions among patients of our cohort. We also aimed to assess drug compliance among our patients.
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