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Malakoplakia Involving the Maxilla: A Case Report and a Review of the Literature.
Head Neck Pathol
June 2024
Division of Dental and Oral Medicine, New York-Presbyterian/Queens, Flushing, New York, USA.
Article Synopsis
- Malakoplakia is a rare inflammatory disorder mainly seen in immunocompromised patients, characterized by an inability of macrophages to effectively kill bacteria.
- Although it usually occurs in the genitourinary and gastrointestinal regions, this report highlights a rare case where malakoplakia affected the maxilla and maxillary alveolar ridge mucosa, marking a unique instance of oral cavity involvement.
- Diagnostic stains revealed specific patterns indicating malakoplakia without evidence of microbial infection, emphasizing the need for clinicians and pathologists to consider this condition when evaluating lesions in immunosuppressed patients.
Clinical Evaluation and Surgical Management of Ocular Malakoplakia of the Caruncle and Periorbital Region: A Report of Two Case and Literature Review.
Ophthalmic Plast Reconstr Surg
July 2024
Department of Pathology, Bangalore Medical College and Research Institute, India.
Article Synopsis
- Ocular malakoplakia is a rare inflammatory disorder identified by the presence of Michaelis-Gutmann bodies, showcased in two unique cases involving the orbit and caruncle.
- The first case features a 10-year-old girl with swelling near the caruncle, where surgical excision confirmed malakoplakia and offered symptom relief.
- The second case is a 23-year-old woman with a swelling thought to be lymphoma, which after biopsy turned out to be malakoplakia, illustrating the need for accurate diagnosis in such uncommon conditions.
18F-FDG PET/CT in a Patient With Epididymo-Testicular Malacoplakia.
Clin Nucl Med
October 2023
Department of Nuclear Medicine, Peking University First Hospital, Beijing, China.
A 56-year-old man presented with a 2-month history of a mass in the right epididymo-testicular region, which exhibited heterogeneous high avidity for 18F-FDG on PET/CT. Malignant tumor was highly suspected, leading to subsequent right orchiectomy and epididymectomy. Histopathological examination revealed the presence of characteristic Michaelis-Gutmann bodies within von Hansemann macrophages, confirming the diagnosis of malacoplakia.
View Article and Find Full Text PDFA case of canine intestinal malakoplakia.
J Comp Pathol
August 2023
Department of Animal Pathology, University of Zaragoza, 177 Miguel Servet Street, 50013 Zaragoza, Spain.
Malakoplakia is a rare chronic granulomatous disease usually affecting the urinary bladder and other locations. In humans, the gastrointestinal tract is the second most common location but there are no reports of intestinal malakoplakia in animals. A 10-month-old female French Bulldog was presented with chronic haemorrhagic diarrhoea and anorexia with normochromic-normocytic anaemia and hypoalbuminaemia.
View Article and Find Full Text PDFMalakoplakia with aberrant ALK expression by immunohistochemistry: a case report.
Diagn Pathol
August 2023
Department of Laboratory Medicine, Panyu District Central Hospital, Guangzhou, China.
Background: Malakoplakia is a rare inflammatory disease of the urogenital tract. There have been no reports of malakoplakia expressing anaplastic lymphoma kinase (ALK) to date. Here, we present one case of malakoplakia with aberrant ALK expression by immunohistochemistry and discuss the clinical significance.
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