Purpose: The purpose of this study was to examine the status of the retina and the choroid, and to evaluate blood flow velocity in the central retinal (CRA) and ophthalmic artery in Behçet's disease.
Methods: Digital fluorescein and indocyanine green (ICG) videoangiography were performed in 53 eyes and color Doppler ultrasonography in 61 eyes of 31 Behçet patients, between December 1993-January 1996.
Results: Fluorescein angiography revealed no vascular leakage in 7, and diffuse retinal and/or disc leakage due to vasculitis in 46 eyes. ICG angiography was normal in 14 eyes while it revealed hypo or hyperfluorescence in the remaining. For the CRA, peak systolic and end diastolic velocities were significantly lower in Behçet patients than in control cases. In the Behçet group, Doppler indices did not differ significantly in eyes which had choroidal abnormalities and those that did not, according to ICG angiography.
Conclusion: In Behçet's disease, some abnormalities in the choroid may be seen. The disease appears to be associated with decreased mean flow velocities in CRA.
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http://dx.doi.org/10.1034/j.1600-0420.1999.770418.x | DOI Listing |
Ocul Immunol Inflamm
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Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Birdshot chorioretinopathy (BSCR) is a bilateral, chronic posterior uveitis with characteristic clinical and imaging findings. Multimodal imaging including optical coherence tomography, fluorescein, and indocyanine green angiography is useful in diagnosis, as well as monitoring disease activity. Cystoid macular edema, choroidal thickening and infiltration, ellipsoid loss, and vasculitis are important imaging markers for disease activity.
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Theranostics
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State Key Laboratory of Vaccines for Infectious Diseases, Center for Molecular Imaging and Translational Medicine, Xiang An Biomedicine Laboratory, National Innovation Platform for Industry-Education Integration in Vaccine Research, School of Public Health, Xiamen University, Xiamen 361002, China.
Recent innovations in medical imaging technology have placed molecular imaging techniques at the forefront of diagnostic advancements. The current research trajectory in this field aims to integrate personalized molecular data of patients and diseases with traditional anatomical imaging data, enabling more precise, non-invasive, or minimally invasive diagnostic options for clinical medicine. This article provides an in-depth exploration of the basic principles and system components of optical molecular imaging technology.
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