Cellular content of neuron populations of cortex, subcortical structures of brain and cerebellum and nuclei of anterior horns of cervical region of the spinal cord was studied in albino and grey rats. The revealed distinctive features of the tinctorial properties and sizes of neurons of different structures of the motor analyser are explained as an adaptation peculiarities of the animal brain organization. Heterogeneity of neuron population at different levels of the brain motor system indicates the different adaptation mechanisms of albino and grey rats.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Griscelli syndrome: Erdheim-Chester disease-like local presentation progressing to accelerated phase.
Turk J Pediatr
November 2024
Division of Pediatric Immunology, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Türkiye.
Background: Griscelli syndrome (GS) is a rare genetic disorder characterized by oculocutaneous albinism and variable immune dysfunction. Among three distinct types of GS, occurring due to different genetic mutations; GS type 1 presents with neurological manifestations, hemophagocytic lymphohistiocytosis (HLH) generally develops in GS type 2, and GS type 3 primarily exhibits oculocutaneous albinism. HLH, a life-threatening condition with excessive immune activation, may occur secondary to various triggers, including infections, and develop in different tissues, as well as in the testis, similar to Erdheim-Chester disease.
View Article and Find Full Text PDFRole of Morphology in the Diagnosis of an Unsuspected Case of Chediak-Higashi Syndrome: A Case Report.
Cureus
December 2024
Department of Pathology, Ranga Raya Medical College, Kakinada, IND.
Chediak-Higashi syndrome (CHS) is a rare multisystem genetic disorder of childhood, caused by a defect in vesicular trafficking, which is an essential process for intracellular transport. This defect results in the formation of giant cytoplasmic granules in various cell types, including white blood cells, melanosomes, and Schwann cells. The presence of giant lysosomal granules in neutrophils and their precursors is a distinct and diagnostic feature of CHS, differentiating it from other childhood immunodeficiency disorders, such as Griscelli syndrome and Hermansky-Pudlak syndrome, which share common characteristics like albinism and increased susceptibility to fatal hemophagocytic lymphohistiocytosis.
View Article and Find Full Text PDFComparative transcriptome analysis of albino northern snakehead (Channa argus) reveals its various collagen-related DEGs in caudal fin cells.
PLoS One
December 2024
College of Life Sciences, Neijiang Normal University, Neijiang, China.
The albino northern snakehead (Channa argus) is an aquaculture species characterized by heritable albino body color, in contrast to the typical coloration. Additionally, there are gray- and golden-finned individuals, which exhibit distinct coloration in their caudal fins. We performed RNA-seq to profile the transcriptome of caudal fin tissues in albino gray-finned and golden-finned C.
View Article and Find Full Text PDFGriscelli syndrome: a diagnostic challenge of a rare disease: a case report.
Ann Med Surg (Lond)
October 2024
Department of Gastroenterology & Interventional Endoscopy Pediatric, Damascus University, Pediatric Hospital and Syrian Specialty Hospital, Damascus, Syria.
Introduction: Griscelli syndrome (GS) is a rare autosomal recessive genetic disorder that primarily manifests as hair and skin hypopigmentation, with three types differentiated by their specific genetic defects as well as by their clinical features. Clinically, GS type 1 is characterized by early neurological alterations, while GS type 2 is characterized by immunodeficiency and could present with neurological symptoms, and type 3 is characterized by a chromosomal anomaly without a specific clinical profile besides hypopigmentation. This article details the challenges faced in the diagnosis of a patient with GS who presents with neurological symptoms followed by immunological deficits.
View Article and Find Full Text PDFAlbinism and Blood Cell Profile: The Peculiar Case of Asinara Donkeys.
Animals (Basel)
September 2024
Istituto Zooprofilattico Sperimentale della Sardegna "G. Pegreffi", 07100 Sassari, Italy.
Article Synopsis
- A study analyzed the complete blood cell counts (CBC) of 15 donkeys, comparing 8 Asinara breed donkeys (with oculocutaneous albinism) and 7 Sardo breed donkeys, all under the same conditions and monitored in June 2024.
- Asinara donkeys had significantly higher red blood cell (RBC) counts than Sardo donkeys, showing RBCs with smaller diameters and more variation in size (anisocytosis).
- Although all donkeys appeared healthy, Sardo donkeys showed mild eosinophilia, while the unique hematological traits of the Asinara breed were noted, particularly during the positive photoperiod.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!