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Probiotics interventions modulating gut microbiota composition in individuals with intestinal constipation: Protocol of a systemic review and meta-analysis of randomized controlled trials.
PLoS One
January 2025
Department of Anorectal Surgery, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Introduction: Intestinal constipation is a substantive global health concern, significantly impairing patient quality of life. An emerging view is that the gut microbiota plays a critical role in intestinal function, and probiotics could offer therapeutic benefits. This study aims to consolidate evidence from randomized controlled trials (RCTs) that assess the effectiveness of probiotics in modulating microbiota and ameliorating symptoms of constipation.
View Article and Find Full Text PDFRejunctive Moves Toward Systemic Healing: A Contextual Family Therapy Approach to Father's Absence.
Fam Process
March 2025
Couple and Family Therapy Program, Alliant International University, Irvine, California, USA.
The phenomena of father's absence and the disruption of a family unit due to social justice issues like incarceration and mental health/substance misuse challenges are widely documented, and their effects on the whole family are well established in the literature. This paper specifically examines how systemic inequities like racism contribute to destructive entitlements that can occur transgenerationally within families affected by father's absence. The consideration of racial trauma is crucial, as father's absence and family disruption are not limited to any one racial or ethnic group, but the effects are often exacerbated for families of color due to the intersecting impacts of systemic racism.
View Article and Find Full Text PDFOrganoid Ethical Typology: varieties of three-dimensional stem cell constructs and the many issues they raise in bioethics.
Biol Cell
January 2025
Institut supérieur de philosophie, UCLouvain, Louvain-la-Neuve, Belgium.
The advancement of and prospects for stem cell research raise a number of specific ethical issues. While navigating the ethical landscape of stem cell research is often challenging for biology researchers and biotechnology innovators, it is also difficult for the public and other persons of concern (from ethicists to policy-makers) to grasp the technicalities of a burgeoning field that develops in many directions. Organoids are one of these new biotechnological constructs that are currently eliciting a rich debate in bioethics.
View Article and Find Full Text PDFCommunicating scientific evidence: drugs for Alzheimer's disease as a case study.
Curr Med Res Opin
January 2025
Laboratory of Behavioral Neuroscience, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.
This paper reviews the scientific evidence on new anti-amyloid monoclonal antibodies for treating Alzheimer's disease as a case study for improving scientific evidence communication. We introduce five guidelines condensed from the biomedical evidence literature but adapted to the short format of science communication in e.g.
View Article and Find Full Text PDFWhy Ethics Matters Even More in 2025.
Dimens Crit Care Nurs
January 2025
Kathleen Ahern Gould, PhD, RN, Editor in Chief, Dimensions of Critical Care Nursing, Duxbury, Massachusetts.
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