Cysteine cathepsin L was isolated and purified 1242-fold from human brain. Cathepsin L pH-optimum, Vmax, K(m), lysosomal origin and thiol nature were determined. The distribution of cathepsin L activity in human brain tumours of different histological structure, histogenesis and degree of malignization was studied. The activity of cathepsin L in most the tumours was found to be higher compared to the normal brain tissue.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
human brain
12
[cathepsin human
4
brain
4
brain tumor
4
tumor purification
4
purification contents]
4
contents] cysteine
4
cathepsin
4
cysteine cathepsin
4
cathepsin isolated
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!