Objective: Histoplasma capsulatum infection is considered to be endemic in the West Indies. Nevertheless, few epidemiologic studies have been conducted in this area. The histoplasmin skin test reflects the frequency of asymptomatic forms of histoplasmosis. We studied the prevalence of positive skin tests in a population of the French West Indies (Martinique).
Materials And Methods: Forty one patients (24 females and 17 males), age range 29 to 90 years, were tested for histoplasmin skin sensitivity between August and October 1997, in the department of dermatology of Fort de France (French West Indies). Patients with immunosuppression or personal history of histoplasmosis were excluded.
Results: Five patients had a positive skin test (12 p. 100). No significative association was found between a positive skin test and diabetes, rural occupations or exposure to bats.
Discussion: Despite the small number of cases, related with difficulties in obtaining histoplasmin, our study showed a sensitivity level similar to medium endemic areas of the USA. The positive skin test rate is much higher than the rate reported before in West Indies, in a sample of the population under 25 years of age.
Download full-text PDF |
Source |
---|
HCA Healthc J Med
December 2024
St George's University, Grenada, West Indies.
Background: The United States Food and Drug Administration approved 6 atypical antipsychotics for pediatric treatment of schizophrenia. However, little has been published on the effectiveness of these medications in the acute treatment setting of adolescents with psychosis. Since the clinical uncertainty and poor prognosis proceeding the early onset of schizophrenia has a significant impact on a child's development, there is a critical need for evidence-based data on this population.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
DIAN-TU.Knight Alzheimer's Disease Research Center, St. Louis, MO, USA.
Background: While two-thirds of the 57 million people with dementia worldwide live in low- and middle-income countries, research to inform dementia-related policy in these regions remains scarce. We aimed to increase early dementia diagnosis and the use of standardized cognitive assessment by PCP in primary care settings in Cuba METHOD: We selected 16 Primary care clinics, with an estimated 160-200 providers. Clinics were carefully paired based on a number of providers, population demographics, and baseline rates of cognitive impairment diagnosis before being randomized into two groups: one to receive a targeted intervention and the other to continue with usual care practices.
View Article and Find Full Text PDFBackground: This study aimed to assess associations between socioeconomic condition and cognitive function among Puerto Rican adults residing in the greater Boston Area.
Methods: We assessed the relationship between a score of social condition, encompassing education, income-to-poverty ratio, perceived stress, food security, and psychological acculturation, and cognitive function in a cohort of Puerto Rican Adults residing in the greater Boston area. The score was assessed over more than 12 years of follow-up and ranged from 0 (best social condition) to 15 (poorest social condition).
Background: In the United States and Puerto Rico, cognitive decline and resulting Alzheimer's disease are major public health concerns for older adults. According to the Alzheimer's Association (2021), by 2050, people ages 65 and above with Alzheimer's are estimated to grow to 12.7 million-rising in prevalence and severity.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians & Surgeons, Columbia University, New York, NY, USA.
Background: Hispanics, one of the fastest-growing populations in the United States, are disproportionately affected by Alzheimer's disease (AD). Understanding the variations in AD risk associated with sex and the impact of relocation from their home country is crucial in designing interventions to address health disparities. This study explores the differential impact of sex and geographic relocation on dementia risk and its associated factors among Hispanics.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!