Objectives: An analysis of the results achieved with intracordal autologous fat injection for unilateral laryngeal nerve paralysis after surgery.
Patients And Method: A study group of 46 patients with unilateral laryngeal nerve paralysis was treated by intracordal injection of autologous fat with a minimum follow-up of eight months. All patients had severe dysphonia and 39 had breathlessness. Twenty-nine patients had aspiration problems with difficulties in swallowing.
Results: The only adverse side-effect was a subcutaneous abdominal hematoma in two patients and the development of an intracordal cyst in two patients. Aspiration disappeared immediately after the intracordal injection. Immediate improvement of speech, cough, and breathlessness was achieved in all patients. Over time, speech and voice, and swallowing remained stable in 67% and 80% of patients, respectively.
Conclusion: Such data suggest that the intracordal injection of autologous fat is a valuable method in patients with unilateral laryngeal nerve paralysis after surgery.
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http://dx.doi.org/10.1016/s0001-4001(99)80094-4 | DOI Listing |
J Clin Med
December 2024
Department of Surgery, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Miyagi, Japan.
Recurrent laryngeal nerve palsy remains a significant complication following minimally invasive esophagectomy for esophageal cancer. Despite advancements in surgical techniques and lymphadenectomy precision, the incidence of recurrent laryngeal nerve palsy has not been improved. Recurrent laryngeal nerve palsy predominantly affects the left side and may lead to unilateral or bilateral vocal cord paralysis, resulting in hoarseness, dysphagia, and an increased risk of aspiration pneumonia.
View Article and Find Full Text PDFJ Voice
December 2024
Tokyo Voice Center, International University of Health and Welfare, Tokyo, Japan; School of Medicine, International University of Health and Welfare, Narita, Japan.
Objective: To identify factors correlated with the effect of intracordal trafermin injection.
Study Design: Retrospective cohort study.
Methods: Herein, 177 patients who received an intracordal trafermin injection at the Tokyo Voice Center for vocal fold paralysis were included.
Laryngoscope
January 2025
Department of Otolaryngology-Head and Neck Surgery, NYU Grossman School of Medicine, New York, New York, U.S.A.
Eur Arch Otorhinolaryngol
October 2024
Department of Surgery, University of Auckland, Private Bag 91019, Grafton Auckland, New Zealand.
Am J Otolaryngol
March 2024
Tokyo Voice Center, International University of Health and Welfare, Tokyo, Japan. Electronic address:
Introduction: Mutational voice disorder is the inability of the voice to adjust to the changes in the larynx during puberty, resulting in the speaking fundamental frequency failing to decrease. Standard treatments for mutational voice disorder are voice therapy and thyroplasty. However, voice therapy takes time to show its effects, and thyroplasty is highly invasive.
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