Beta-amyloid: Alzheimer's disease and brain beta-amyloidoses.

Biochemistry (Mosc)

Institute of Biomedical Chemistry, Russian Academy of Medical Sciences, Moscow, 119832, Russia.

Published: July 1999

This review considers some aspects of the biochemistry of beta-amyloid, a protein which produces insoluble deposits in the brain. These deposits are a specific morphological feature of Alzheimer's disease, Down's syndrome, and senile dementia. Our contribution to the concept of a soluble form of beta-amyloid as of a normal human protein is presented.

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