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A matter of timing: Biting by malaria-infected Anopheles mosquitoes and the use of interventions during the night in rural south-eastern Tanzania.
PLOS Glob Public Health
December 2024
Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.
Knowing when and where infected mosquitoes bite is required for estimating accurate measures of malaria risk, assessing outdoor exposure, and designing intervention strategies. This study combines secondary analyses of a human behaviour survey and an entomological survey carried out in the same area to estimate human exposure to malaria-infected Anopheles mosquitoes throughout the night in rural villages in south-eastern Tanzania. Mosquitoes were collected hourly from 6PM to 6AM indoors and outdoors by human landing catches in 2019, and tested for Plasmodium falciparum sporozoite infections using ELISA.
View Article and Find Full Text PDFSystematic review on the cost of seasonal malaria chemoprevention (SMC).
Malar J
December 2024
Management Sciences for Health, Arlington, VA, USA.
Background: Implemented in 17 countries to date, seasonal malaria chemoprevention (SMC) is a recommended strategy to prevent childhood malaria in areas with seasonal transmission of P. falciparum through monthly administration of antimalarial medicines. Understanding the costs and resource requirements of SMC delivery is necessary for effective planning and resource allocation.
View Article and Find Full Text PDFThe 1,7-malaria reactive community-based testing and response (1,7-mRCTR) approach in Tanzania: a cost-effectiveness analysis.
Infect Dis Poverty
December 2024
Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Background: Reactive case detection (RACD) for malaria control has been found effective in low transmission settings, but its impact and cost-effectiveness in moderate-to-high transmission settings are unknown. We conducted an economic evaluation alongside an empirical trial of a modified RACD strategy (1,7-mRCTR) in three moderate-to-high malaria transmission districts in Tanzania.
Methods: The costs and cost savings associated with the intervention relative to passive case detection alone were estimated in the study sites of Kilwa, Kibiti, and Rufiji districts in Tanzania from 2019-2021.
Cost of the national malaria control program and cost-effectiveness of indoor residual spraying and insecticide-treated bed net interventions in two districts of Madagascar.
Cost Eff Resour Alloc
December 2024
Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Article Synopsis
- * This study analyzed the costs and effectiveness of two malaria control interventions—Insecticide-Treated Nets (ITNs) and Indoor Residual Spraying (IRS)—in two districts, comparing their cost-effectiveness ratios (CERs) to determine the better intervention.
- * From 2009 to 2013, the National Malaria Control Program (NMCP) cost approximately USD 45.4 million annually, with IRS being significantly more expensive than ITNs; the CER for IRS was about six times higher than that of ITNs, indicating that ITNs might be
Evaluating the effectiveness and cost-effectiveness of integrating mass drug administration for helminth control with seasonal malaria chemoprevention in Ghanaian children: Protocol for a cluster randomised controlled trial.
Trop Med Int Health
January 2025
Research and Development Division, Kintampo Health Research Centre, Kintampo, Ghana.
Objectives: To evaluate the effectiveness and cost-effectiveness of integrating seasonal malaria chemoprevention (SMC) with mass drug administration for helminth control among school-aged children living in communities where the burden of malaria and helminths is high in Ghana, West Africa.
Methods: This cluster randomised controlled trial will enrol 1200 children aged 5-10 years. Eligible children randomised to intervention clusters will receive SMC drugs (sulphadoxine-pyrimethamine plus amodiaquine) and anthelminthic drugs for soil-transmitted helminths-(albendazole), and for schistosomiasis (praziquantel), while children randomised to control clusters will receive SMC drugs alone.
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