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Antiinfective and encrustation-inhibiting materials--myth and facts.
Int J Antimicrob Agents
June 2002
Caesar-Center of Advanced European Studies and Research, Friedensplatz 16, D-53111 Bonn, Germany.
Catheters, urethral and ureteral stents and other urological implants are frequently affected by encrustration and infection due to their permanent contact with urine. Indwelling urinary catheters provide a haven for microorganisms and thus require extensive monitoring. Several surface modification techniques have been proposed to improve the performance of devices including the immobilization of biomolecules, the incorporation of hydrophilic grafts to reduce protein adsorption, the creation of hydrophobic surfaces, the creation of microdomains to regulate cellular and protein adhesion, new polymers and antimicrobial coatings.
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