Maintenance of pathogenicity of viable but nonculturable Salmonella typhimurium cells experimentally stressed with UV-C and seawater, was investigated relative to the viability level of the cellular population. Pathogenicity, tested in a mouse model, was lost concomitantly with culturability, whereas cell viability remained undamaged, as determined by respiratory activity and cytoplasmic membrane and genomic integrities.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC91479 | PMC |
http://dx.doi.org/10.1128/AEM.65.7.3229-3232.1999 | DOI Listing |
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