This article explores the buffering effect of social support on depressive symptoms in a community sample of elderly with varying levels of disability. Baseline interviews were conducted in respondents' homes. Results show that higher levels of disability are associated with higher levels of depression. Instrumental support and subjective appraisal of the network are associated with depressive symptoms, but instrumental support has a weak positive correlation, while subjective appraisals show a negative relationship. Social support mitigates the depressive effect of disability only when the network's efforts are appraised positively. However, no such relationship is shown for instrumental support. One's perception of the network's helpfulness appears to be more potent than the actual help provided by friends and family.
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http://dx.doi.org/10.2190/E48R-W561-V7RG-LL8D | DOI Listing |
Infect Prev Pract
September 2024
SARS-CoV-2 Sequencing Consortium, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Background: During the SARS-CoV-2 pandemic, dominant viral variants were repeatedly replaced by new variants with altered properties, frequently changing the dynamics of the infection event, as well as the effectiveness of vaccines and therapeutics. SARS-CoV-2 variant monitoring by whole genome sequencing was established at the University Medical Center Mainz, Germany to support patient management during the pandemic.
Methods: SARS-CoV-2 RNA samples from the University Medical Center were analysed weekly with whole genome sequencing.
Ann Vasc Surg
January 2025
The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, China. Electronic address:
Background: Varicose veins (VVs) are a common chronic venous disorder with a complex pathophysiology involving immune dysregulation, inflammation, and genetic predisposition. This study aims to identify immune-related causal factors in the pathogenesis of VVs using Mendelian randomization (MR).
Methods: A two-sample MR analysis was conducted to assess the causal relationships between immune cell phenotypes and VVs.
Adv Biotechnol (Singap)
July 2024
Department of Medical Instrumental Analysis, Zunyi Medical University, Zunyi, 563099, Guizhou, China.
Militarine is a monomer molecule with abundant and distinctive biological properties, also the lead member of secondary metabolites in Bletilla striata, while its biosynthesis mechanism is still unknown. To improve the production efficiency of militarine, sodium acetate and salicylic acid (SA) were introduced as elicitors into the suspension-cultured callus of B. striata.
View Article and Find Full Text PDFSci Rep
January 2025
School of Management, Shandong Second Medical University, No. 7166, Baotong West Street, Weifang, 261053, Shandong, China.
This study examines the impact of micro-level land prices on corporate carbon emission intensity and identifies the underlying mechanisms. Using a unique dataset of Chinese industrial enterprises from 2000 to 2014, we employ a two-way fixed effects econometric model, alongside instrumental variable and Difference-in-Differences (DID) techniques, to address endogeneity concerns. Our findings reveal that a 1% increase in land prices leads to a 0.
View Article and Find Full Text PDFBMJ Open
January 2025
Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden.
Objective: Delayed neurocognitive recovery, previously known as postoperative cognitive dysfunction, is a common complication affecting older adults after surgery. This study aims to address the knowledge gap in postoperative neurocognitive recovery by exploring the relationship between subjective experiences, performance-based measurements, and blood biomarkers.
Design: Mixed-methods study with a convergent parallel (QUAL+quan) design.
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