A case of fatal generalized Blastomycosis is reported. It was the first case of that mycosis observed in Algeria. The parasitic yeast-like cells of the fungus were seen in pus and tissue sections and Blastomyces dermatitidis cultured from pathological specimens. Yeast-like form was obtained in vitro on Kurung's agar at 37 degrees C. Male hamsters infected with this strain failed to develop an experimental disease. The occurrence and distribution of Blastomycosis in Africa are discussed.
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