Splenectomy was done in 448 patients with various forms of hemolytic anemia. Recovery was noted in 362 patients (of them 143 children) with hereditary microspherocytic hemolytic anemia (HMHA). Of 8 patients with hereditary nonmicrospherocytic hemolytic anemia (HNMHA) one died, in 7 general status had improved. Of 78 patients with autoimmune hemolytic anemia (AIHA) 3 died, in 47 (60%) satisfactory result was noted, general status improved--in 18 (23%). If surgical intervention is indicated the operation for HMHA is radical method of treatment, HNMHA--the selective one, and AIHA--one of the main.
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