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Interaction of Programmed Obesity and Postnatal High Fat Diet but Not (-)-Epicatechin Treatment Modifies Muscle Atrophy Proteins Levels in Male Wistar Rats.
Cell Biochem Biophys
March 2025
Obesity Research Unity, Medicine Faculty, Mexico Autonomous National University, Mexico City, México.
We determine whether the offspring of obese mothers and a postnatal high-fat diet (HFD) modify protein levels related to muscle synthesis (p70S6K-alpha) or atrophy (Murf and MAFbx), and if the administration of (-)-epicatechin (Epi) can modify these alterations. We hypothesized that the ubiquitin ligases Murf and MAFbx would be increased in the obesogenic context, either by in utero obesogenic environment or by a postnatal high-fat diet, while the p70S6K-alpha kinase and its activation might be decreased. Eight groups of six male Wistar offspring formed eight experimental groups: control (C), control fed with HFD (CHFD), maternal obesity (MO), maternal obesity fed with HFD (MOHFD), and the groups with Epi intervention: C+Epi long, CHFD+Epi long, MO+Epi long and MOHFD+Epi long.
View Article and Find Full Text PDFLack of Evidence for Omega-3 Fatty Acid Supplementation in Enhancing Lean Mass, Muscle Strength, and Physical Function in Healthy Adults and Clinical Populations: An Overview of Reviews.
Clin Nutr ESPEN
March 2025
McMaster University, Hamilton, ON, CANADA. Electronic address:
Background & Aims: N-3 (omega-3) polyunsaturated fatty acids (n-3-PUFA) have been hypothesized to enhance/maintain skeletal muscle mass, strength, and physical function. We conducted an overview of reviews of n-3 fatty acid monotherapy supplementation and examined whether the evidence supports the effects in healthy young and old adults and clinical populations.
Methods: In line with the PRISMA guidelines, a widely accepted framework for conducting and reporting systematic reviews, we conducted a comprehensive search for systematic reviews (OVID, Embase, Web of Science, SPORTDiscus) reporting the effect of n-3 fatty acid supplementation in our target populations.
Analysis of the Influence of the SARS-CoV-2 (COVID-19) Pandemic on the Search for Facial Aesthetic Procedures.
J Craniofac Surg
March 2025
Department of Oral Surgery, Stomatology, Oral Pathology and Oral Radiology, Bauru School Dentistry, University Of São Paulo, Bauru, Brazil.
The SARS-CoV-2 (COVID-19) pandemic caused, in 2020, a serious and urgent health issue worldwide, establishing social distancing rules, which changed daily life in all its aspects. Work relationships and socialization became possible only through virtual networks. As a result, there has been an extreme increase in the exposure of people in general to their own image for many hours a day through cameras and video conferencing applications.
View Article and Find Full Text PDFTegoprazan-Containing Versus Proton Pump Inhibitor-Containing Therapy for First-Line Eradication of : A Meta-Analysis of Randomized Controlled Trials.
JGH Open
March 2025
Division of Gastroenterology, Department of Internal Medicine Faculty of Medicine Universitas Indonesia-Ciptomangunkusumo General Hospital Jakarta Indonesia.
Introduction: Concerns have been raised regarding the decreasing success rates of the standard treatment of (proton pump inhibitor (PPI) and two/three antibiotics) and the long-term effects carried by PPI. Despite conflicting data, Tegoprazan, a potassium-competitive acid blocker, is hypothesized to be superior to PPI for eradicating . This systematic review and meta-analysis aim to determine the superiority of Tegoprazan-containing therapy to PPI-containing therapy for eradication.
View Article and Find Full Text PDFDoes outdoor air pollution cause poor semen quality? A systematic review and meta-analysis.
BMC Urol
March 2025
Infertility and Reproductive Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Introduction: It is hypothesized that air pollutants could be associated with semen parameters. This systematic review and meta-analysis of observational studies was conducted to reach a firm conclusion regarding the possible association between outdoor air pollution and semen parameters among the adult population.
Methods: PubMed, Scopus, and ISI Web of Science were systematically searched using the text keywords and MeSH terms, including "air pollution" and "semen parameters,".
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