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Development of a dual PM sampling and direct exposure system incorporated an in vitro air-liquid interface culture method: Application to the northern Thailand haze season.
Environ Pollut
December 2024
Biomedical Engineering Institute, Chiang Mai University, Chiang Mai, 50200, Thailand; Biomedical Engineering and Innovation Research Center, Chiang Mai University, Chiang Mai, 50200, Thailand. Electronic address:
Exposure to ambient air pollution is associated with several noncommunicable diseases, and it adversely affects the respiratory system and other organ systems. Several studies have investigated the underlying mechanisms of biological response to air pollutants using conventional techniques, but there is a lack of research on the effects of air pollution at the cellular level. This study developed a dual system that combines PM (particulate matter <2.
View Article and Find Full Text PDFTopical losartan ophthalmic drops - a review of corneal wound healing and topical losartan for managing corneal haze and potential future indications.
Graefes Arch Clin Exp Ophthalmol
December 2024
Instituto de Microcirugía Ocular (IMO) Barcelona Grupo Miranza, Barcelona, Spain.
Article Synopsis
- - Corneal haze results from abnormal healing processes following injuries or surgeries, causing vision impairment due to eye opacity and irregularities, often linked to myofibroblast formation triggered by inflammation.
- - Major causes of corneal haze include surgical procedures like PRK and LASIK, as well as non-surgical factors such as trauma and infections, with research focusing on the TGFβ pathway and inflammation management methods.
- - Losartan, usually used for treating high blood pressure, shows promise in ophthalmology for reducing corneal fibrosis after various injuries and surgeries, leading to this review of its effectiveness and potential future applications in treating corneal haze.
Early visual and clinical outcomes of transepithelial photorefractive keratectomy versus transepithelial keratectomy with smart pulse technology for myopia.
Oman J Ophthalmol
October 2024
Ophthalmology Resident, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Purpose: The purpose of this study was to compare early visual outcomes, epithelial healing, and stromal haze between transepithelial photorefractive keratectomy (Trans-PRK) using smart pulse technology (SPT) with traditional Trans-PRK.
Methodology: This study is a retrospective, comparative study conducted at a private eye center in "Riyadh, Saudi Arabia," investigating myopic patients who underwent either Trans-PRK with SPT (study group) or traditional Trans-PRK (control group). The patients were assessed preoperatively and followed up at 1 week and 2 months postoperatively.
Outcomes of pediatric sterile keratitis posthypotonic collagen cross-linking.
Oman J Ophthalmol
October 2024
Cornea and Anterior Segment, Shantilal Shanghvi Cornea Institute, L V Prasad Eye Institute, Vijayawada, Andhra Pradesh, India.
In this case series, we will describe sterile keratitis in the early postoperative period after hypotonic collagen cross-linking (CXL) in two pediatric cases. This is a retrospective case series of two eyes of two children who developed inflammatory keratitis with central corneal haze after uneventful epithelial-off hypotonic CXL. After ensuring microbiological sterility, appropriate treatment with topical steroids and lubricants was started.
View Article and Find Full Text PDFClinical Outcomes of Infectious Keratitis Associated with Contact Lens Wear Following Penetrating Keratoplasty: A Case Series.
Int Ophthalmol
November 2024
Department of Ophthalmology and Visual Neurosciences, University of Minnesota, 516 Delaware St SE, Minneapolis, MN, 55455, USA.
Purpose: To report on the clinical characteristics, and outcomes of patients who developed infectious keratitis associated with contact lens (CL) wear following penetrating keratoplasty (PK).
Methods: A retrospective chart review was performed to identify all patients who underwent PK between November 2012 and January 2023 at a single tertiary referral practice, and subsequently developed CL related infectious keratitis. 74 patients using CL following PK were identified.
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