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| http://dx.doi.org/10.1136/gut.44.4.579 | DOI Listing |
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Obstructive sleep apnea and 19 gastrointestinal diseases: a Mendelian randomization study.
Front Psychiatry
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Department of Otolaryngology, Head and Neck Surgery, Children's Hospital Capital Institute of Pediatrics, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Background: Alterations gastrointestinal diseases (GDs) were reported in individuals with obstructive sleep apnea (OSA), however, the genetic background between OSA and GDs is still unclear.
Methods: This investigation employed Mendelian randomization (MR) analyses to evaluate the causal effect between OSA and 19 types of GDs (gastroesophageal reflux disease (GERD), ulcerative colitis, celiac disease, Crohn's disease, chronic gastritis, irritable bowel syndrome, primary biliary cholangitis, diverticular disease, gastroduodenal ulcer, acute pancreatitis, non-alcoholic fatty liver disease, primary sclerosing cholangitis, cirrhosis, calculus of bile duct, calculus of gallbladder, pancreatic cancer, gastric cancer, colorectal cancer, and esophageal cancer). The inverse-variance weighted (IVW) method was used to evaluate the main effects model of causality.
The potential role of in liver health.
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Shanghai Institute of Materia Medica, Chinese Academy of Sciences, No. 501 Haike Road, Shanghai, 201203, China.
() is a 'star strain' that has attracted much attention in recent years. can effectively regulate host metabolism, significantly affect host immune function, and play an important role in balancing host health and disease. As one of the organs most closely related to the gut (the two can communicate through the hepatic portal vein and bile duct system), liver is widely affected by intestinal microorganisms.
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School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
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View Article and Find Full Text PDFAssociation of MASLD with the risk of extrahepatic cancers: A systematic review and meta-analysis of 18 cohort studies.
Eur J Clin Invest
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View Article and Find Full Text PDF[Clinicopathological features of Sjogren's syndrome complicated with liver injury].
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Department of Pathology, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
To study the clinicopathological features of Sjogren's syndrome (SS) with liver injury and to improve the understanding of this disease. Forty-nine patients with SS complicated with liver injury were collected from Beijing Ditan Hospital, Capital Medical University from October 2008 to January 2022. All patients underwent ultrasound-guided liver biopsy, and all specimens were stained with HE.
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