AI Article Synopsis
- Activated guidewire angioplasty (AGA) is a new approach aimed at improving angioplasty outcomes for total coronary occlusions, utilizing flexible soft guidewires.
- A study involving 73 patients showed a 65.7% success rate in crossing lesions, translating to a 56.1% overall success in performing angioplasty procedures.
- Key predictors of success included the occlusion location (especially in the right coronary artery), male gender, duration and length of occlusions.
Article Abstract
Activated guidewire angioplasty (AGA) is a new technique which has been designed to assist in angioplasty of total occlusions. The purpose of this study was to determine the safety and efficacy of using flexible relatively soft guidewires (floppy wires) in conjunction with this technique and also to determine the predictors of lesion crossing and final success by this technique in patients with chronic total coronary occlusions. 73 patients with 73 chronic total coronary occlusions in whom coronary angioplasty using conventional techniques had failed were treated with AGA using floppy guidewires. The success of crossing these lesions was 65.7% (48/73) resulting in a final angioplasty success of 56.1% (41/73). Angioplasty success was reduced compared with crossing success in seven arteries in which complications occurred during balloon angioplasty. Multiple stepwise logistic regression analysis identified the location of the occlusion (right coronary artery, p = 0.005) as independent predictor of crossing success of this technique and the male gender (p = 0.03), the duration of occlusion (p = 0.05), the lesion length (p = 0.01) and the location of the occlusion (right coronary artery, p = 0.02) as independent predictors of final procedural success of the method.
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| http://dx.doi.org/10.1259/bjr.72.854.10365067 | DOI Listing |
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