Eleven Shigella flexneri (group B) isolates were recovered from epidemiologically linked patrons and food handlers from a restaurant-associated outbreak of shigellosis. Six isolates available for pulsed-field gel electrophoresis were identical. All strains agglutinated in group B and subgroup factor 6 sera but not in group 1 through group 6 sera.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC85161 | PMC |
| http://dx.doi.org/10.1128/JCM.37.7.2352-2353.1999 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Antibacterial, antibiofilm, and gene expression assessment of Ajwain (Trachyspermum ammi) essential oil on drug-resistant gastrointestinal pathogens and its combination effect with ampicillin.
Lett Appl Microbiol
December 2024
Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Essential oils are natural substances used as therapeutic agents and food preservatives to inhibit harmful microorganisms. This study aimed to assess the synergistic effect of Trachyspermum ammi essential oil and ampicillin on antibiotic-resistant gastrointestinal pathogens, including Escherichia coli, Enterococcus faecalis, Shigella flexneri, Salmonella typhimurium. Using gas chromatography-mass spectrometry (GC-MS), the main components of T.
View Article and Find Full Text PDFA newly developed oral infection mouse model of shigellosis for immunogenicity and protective efficacy studies of a candidate vaccine.
Infect Immun
December 2024
Division of Clinical Medicine, ICMR-National Institute of Cholera and Enteric Diseases, Kolkata, West Bengal, India.
infection poses a significant public health challenge in the developing world. However, lack of a widely available mouse model that replicates human shigellosis creates a major bottleneck to better understanding of disease pathogenesis and development of newer drugs and vaccines. BALB/c mice pre-treated with streptomycin and iron (FeCl) plus desferrioxamine intraperitoneally followed by oral infection with virulent resulted in diarrhea, loss of body weight, bacterial colonization and progressive colitis characterized by disruption of epithelial lining, loss of crypt architecture with goblet cell depletion, increased polymorphonuclear infiltration into the mucosa, submucosal swelling (edema), and raised proinflammatory cytokines and chemokines in the large intestine.
View Article and Find Full Text PDFA Recombinant Strain Expressing ETEC Heat-Labile Enterotoxin B Subunit Shows Promise for Vaccine Development via OMVs.
Int J Mol Sci
November 2024
Department of Microbiology and Parasitology, Navarra Medical Research Institute (IdiSNA), University of Navarra, 31008 Pamplona, Spain.
Diarrheal diseases caused by and enterotoxigenic (ETEC) are significant health burdens, especially in resource-limited regions with high child mortality. In response to the lack of licensed vaccines and rising antibiotic resistance for these pathogens, this study developed a recombinant strain with the novel incorporation of the gene for the heat-labile enterotoxin B (LTB) subunit of ETEC directly into 's genome, enhancing stability and consistent production. This approach combines the immunogenic potential of LTB with the antigen delivery properties of outer membrane vesicles (OMVs), aiming to provide cross-protection against both bacterial pathogens in a stable, non-replicating vaccine platform.
View Article and Find Full Text PDFA corollary study to substantiate the therapeutic role of receptor from in mitigating the sperm immobilization factor-mediated negative influences on mouse spermatozoa: a molecular mimicry-based approach.
Reprod Fertil Dev
December 2024
Department of Microbiology, Panjab University, Chandigarh, India.
Context Sperm immobilization factor (SIF) isolated from Staphylococcus aureus has been implicated earlier in the laboratory in infertility due to its negative impact on sperm function. Moreover, SIF was found to bind not only to human and mouse spermatozoa but also to several bacteria. Among the array of bacteria, we selected Shigella flexneri to investigate if it shares antigenic determinants with spermatozoa.
View Article and Find Full Text PDFIn Vitro Biological Activities of an Endophytic Fungus, sp. L2D2 Isolated from .
Indian J Microbiol
December 2024
Department of Life Sciences (Botany), Manipur University, Canchipur, Manipur 795003 India.
The endophytic fungus, sp. L2D2 was isolated from the medicinal plant and has been assessed for extracellular enzyme production, plant growth promotion, antifungal, antibacterial, and antioxidant activities in vitro. The endophyte has been found to produce amylase, cellulose, and ammonia qualitatively.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!