AI Article Synopsis
- Intravascular fasciitis is a rare form of nodular fasciitis found in a 26-year-old man, where a lesion develops within a superficial vein in the forearm.
- The lesion grows along the vein's inner layer and exhibits histology similar to typical nodular fasciitis, with some speculation that specific myofibroblasts are its source.
- Accurate diagnosis is crucial to differentiate it from other vascular lesions, and while excision is usually curative, a couple of recurrence cases have been reported.
Article Abstract
Intravascular fasciitis is a very unusual variant of nodular fasciitis. A unique case of this lesion occurring in the proximal portion of the superficial vein of the forearm in an otherwise healthy 26-year-old man is reported. The intravascular polypoid lesion grew longitudinally along the vascular lumen, was loosely attached to the intimal layer, and was partly anchored beyond the internal elastic lamina into the medial smooth muscle layer. However, extravascular involvement was absent. The histological features were identical to those observed in ordinary cellular nodular fasciitis. Because of its myofibroblastic phenotype exhibited by highly proliferative spindle cells, certain intimomedial myofibroblasts are thought to be the indigenous source of this unique fibroproliferative lesion. Unless the diagnosis of intravascular fasciitis is considered and appropriate differential markers examined, it may be confused with other intravascular lesions, such as intravascular leiomyoma, intravenous pyogenic granuloma, organized thrombus and, even, fibromuscular dysplasia if it arises in the arteries. A simple excision is considered curable. Even so, two recurrent cases have been documented to date.
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| http://dx.doi.org/10.1046/j.1440-1827.1999.00842.x | DOI Listing |
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Article Synopsis
- Intravascular fasciitis (IF) is a rare but benign condition that occurs in the fascia surrounding small to medium blood vessels.
- An 8-year-old boy with swelling in the groin was found to have a deep vein thrombosis but later developed an unusual mass, leading to the discontinuation of treatment with anticoagulants.
- After surgery and examination, the mass was identified as intravascular fasciitis, highlighting the need for doctors to differentiate IF from more serious conditions like sarcoma and thrombosis.
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