Presept (containing sodium dichloroisocyanurate as active component) was shown to be an excellent analytical reagent superior to classical Chloramine T and Chloramine B. Potentiometric titration of potassium ferrocyanide was found to be most suitable for estimation of chlorine content in Presept solutions. The presence of serum albumin can block or reverse the oxidation of ferrocyanide completely, whereas that of a detergent is of little importance. The content of available chlorine in various Presept tablets was found to be as a rule slightly higher than that guaranteed by the dilution rules of Johnson & Johnson. Presept solutions are remarkably stable, paradoxically the concentration of available chlorine in open vessels remains higher than in perfectly closed vessels.
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