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Pityriasis Rubra Pilaris and underlying malignancy.
QJM
October 2024
Department of Dermatology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, China.
A 59-year-old man presented with a five-month history of widespread, salmon-colored, scaly plaques. Skin examination revealed salmon-colored plaques with "islands of sparing" on the trunk and waxy keratoderma on the palms and soles. Histopathology of the lesion showed alternating orthokeratosis and parakeratosis in vertical and horizontal directions, consistent with a diagnosis of pityriasis rubra pilaris (PRP).
View Article and Find Full Text PDFSevere pityriasis rubra pilaris complicated with Kaposi's varicelliform eruption and cutaneous MRSA infection case report.
Heliyon
July 2024
Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, LT-01513, Vilnius, Lithuania.
Article Synopsis
- A 62-year-old woman had serious skin problems called erythroderma, which affected her whole body and started as psoriasis six months before.
- Despite treatments like topical creams and oral medication, her condition got worse with new skin lesions, hair loss, and nail changes.
- After treating her with strong medication and antibiotics, she improved, and by her follow-up visit nearly a year later, her skin was almost all better.
Paraneoplastic Cutaneous Manifestations of Hepatocellular Carcinoma. A Systematic Review and Meta-analysis.
J Cancer
January 2024
Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, ON. Canada.
Article Synopsis
- - A systematic review analyzed 48 studies involving 60 patients with hepatocellular carcinoma (HCC) and their associated skin conditions, revealing a lack of data on the clinical significance of these paraneoplastic skin manifestations.
- - The most common skin issues observed included dermatomyositis, pityriasis rotunda, and porphyria, with dermatomyositis linked to viral hepatitis and other conditions tied to metabolic causes of HCC.
- - The study found that paraneoplastic skin changes were more prevalent in metastatic cases, with differing prognostic implications; particularly, pityriasis rotunda showed a lower risk of death compared to dermatomyositis.
A case of paraneoplastic pityriasis rubra pilaris.
JAAD Case Rep
September 2023
Department of Dermatology, University of North Carolina School of Medicine, Chapel Hill, North Carolina.
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