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| http://dx.doi.org/10.1136/jnnp.66.6.797 | DOI Listing |
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The effect of selective surface interaction on polymer phase separation with explicit polydispersity during polymerization.
Soft Matter
January 2025
Department of Chemical and Biomolecular Engineering, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA.
In polymerization-induced phase separation, the impact of polymer-substrate interaction on the dynamics of phase separation for polymer blends is important in determining the final morphology and properties of polymer materials as the surface can act as another driving force for phase separation other than polymerization. We modify the previously-developed polymerizing Cahn-Hilliard (pCH) method by adding a surface potential to model the phase separation behavior of a mixture of two species independently undergoing linear step-growth polymerization in the presence of a surface. In our approach, we explicitly model polydispersity by separately considering different molecular-weight components with their own respective diffusion constants, and with the surface potential preferentially acting on only one species.
View Article and Find Full Text PDFMapping Activity and Functional Organisation of the Motor and Visual Pathways Using ADC-fMRI in the Human Brain.
Hum Brain Mapp
February 2025
Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.
In contrast to blood-oxygenation level-dependent (BOLD) functional MRI (fMRI), which relies on changes in blood flow and oxygenation levels to infer brain activity, diffusion fMRI (DfMRI) investigates brain dynamics by monitoring alterations in the apparent diffusion coefficient (ADC) of water. These ADC changes may arise from fluctuations in neuronal morphology, providing a distinctive perspective on neural activity. The potential of ADC as an fMRI contrast (ADC-fMRI) lies in its capacity to reveal neural activity independently of neurovascular coupling, thus yielding complementary insights into brain function.
View Article and Find Full Text PDFDeep learning algorithms for predicting pathological complete response in MRI of rectal cancer patients undergoing neoadjuvant chemoradiotherapy: a systematic review.
Int J Colorectal Dis
January 2025
Colorectal Section, Department of Surgery, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Purpose: This systematic review examines the utility of deep learning algorithms in predicting pathological complete response (pCR) in rectal cancer patients undergoing neoadjuvant chemoradiotherapy (nCRT). The primary goal is to evaluate the performance of MRI-based artificial intelligence (AI) models and explore factors affecting their diagnostic accuracy.
Methods: The review followed PRISMA guidelines and is registered with PROSPERO (CRD42024628017).
Newly developed DWI hyperintensities and changes in cerebral blood flow after carotid stent placement for unilateral symptomatic carotid artery stenosis.
Medicine (Baltimore)
January 2025
Department of Neurology, Haiyan People's Hospital Jiaxing, Zhejiang, China.
This study aimed to evaluate changes in cerebral blood flow and perioperative outcomes in patients with unilateral symptomatic carotid artery stenosis before and after carotid artery stenting (CAS), providing insights to guide surgical decision-making. Ninety-six patients with moderate to severe unilateral symptomatic carotid artery stenosis (>50%) admitted to the Neurology Department of the Second Affiliated Hospital of Zhejiang University from June 2023 to April 2024 were included. All patients underwent CAS and magnetic resonance imaging, including diffusion-weighted imaging (DWI) and 3D quasi-continuous arterial spin-labeled perfusion imaging, within 3 days preoperatively and on the third postoperative day.
View Article and Find Full Text PDFIntroducing the Caliber-Flow Status Scale (CFSS): a novel tool for assessing covered cortical branch status after flow diverter treatment of middle cerebral artery aneurysms.
J Neurointerv Surg
January 2025
Neuroradiology, Université Reims-Champagne-Ardenne, Hôpital Maison Blanche, Reims, France
Background: This study assessed caliber and flow changes of covered cortical middle cerebral artery (MCA) branches using the new Caliber-Flow Status Scale (CFSS), postoperative diffusion-weighted imaging (DWI) lesions, and clinical outcome following flow diverter (FD) treatment of MCA aneurysms.
Methods: This single-center retrospective study collected data from patients treated with FD between January 2016 and March 2024, including patient characteristics, aneurysm features, postoperative DWI lesions, and clinical outcomes. Vessel status was assessed using CFSS: 1a (normal caliber and flow), 1b (normal caliber, reduced flow), 2a (reduced caliber, normal flow), 2b (reduced caliber and flow), and 3 (occlusion).
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