It has been suggested that the short-term clinical outcome of schizophrenia may be better in developing than in industrialised countries. Little is known of the social outcome of the disorder in the medium term in developing societies. In a study of 120 clinically stable outpatients in a clinic in Nigeria, we examined the social, occupational and residential outcomes of schizophrenia after 13 years. A substantial proportion of patients showed a moderate to severe degree of disability in the areas of occupation and social contact. Four percent were homeless or of unstable abode. While men were particularly disadvantaged in establishing a marital relationship and also evidenced impaired fecundity, women had a more impaired outcome in the domain of frequency and quality of social contact. Poor response to initial treatment and indices of impaired premorbid adjustment were associated with poor outcome 13 years after illness onset. Even though these patients had come predominantly from low social (and occupational) groups, they still manifested a downward drift on the social ladder. In the medium to long term, traditional family networks may be inadequate to prevent patients with schizophrenia in developing societies from acquiring significant and multiple disablement.
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http://dx.doi.org/10.1007/s001270050126 | DOI Listing |
Eur J Pediatr
January 2025
Global Health and Tropical Medicine, GHTM, LA-REAL, Instituto de Higiene e Medicina Tropical, IHMT, Universidade NOVA de Lisboa, Lisbon, Portugal.
Purpose: Under-five mortality is a key public health indicator, highly responsive to preventive interventions. While global efforts have made strides in reducing mortality rates in this age group, significant disparities persist, particularly in Sub-Saharan Africa. This study aimed to systematically review the factors influencing under-five mortality in Africa, focusing on sociodemographic factors and health-related determinants.
View Article and Find Full Text PDFJ Gen Intern Med
January 2025
Center for Health Equity Research and Promotion, Crescenz VA Medical Center, Philadelphia, PA, USA.
Background: Healthcare-based social need screening and referral (S&R) among adult populations has produced equivocal results regarding social need resource connection.
Objective: Assess the efficacy of S&R on resource connection (primary outcome) and unmet need reduction (secondary outcome).
Design: Intention-to-treat randomized controlled trial.
Diabetologia
January 2025
MRC Epidemiology Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
Aims/hypothesis: UK standard care for type 2 diabetes is structured diabetes education, with no effects on HbA, small, short-term effects on weight and low uptake. We evaluated whether remotely delivered tailored diabetes education combined with commercial behavioural weight management is cost-effective compared with current standard care in helping people with type 2 diabetes to lower their blood glucose, lose weight, achieve remission and improve cardiovascular risk factors.
Methods: We conducted a pragmatic, randomised, parallel two-group trial.
Sci Rep
January 2025
The PRIDE Study/PRIDEnet, Stanford University School of Medicine, Stanford, CA, USA.
Structural stigma towards gender minority (GM; people whose current gender does not align with sex assigned at birth) people is an important contributor to minority stress (i.e., stress experienced due to one's marginalized GM identity), although existing variables are unclear in their inclusion of social norms, or societal stigma, as a key component of the construct.
View Article and Find Full Text PDFSleep Health
January 2025
Unit of Population Epidemiology, Division of Primary Care, Geneva University Hospitals, Geneva, Switzerland; Department of Health and Community Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland; School of Population and Public Health, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Background: Social inequalities in sleep have been reported, but there is less research on the mechanisms underlying this association. This study investigates the relationship between financial hardship and sleep within the general adult population, focusing on the mediating effects of psychosocial and lifestyle-related factors.
Methods: We used data from the Specchio cohort, a population-based study in Geneva, Switzerland, initiated in December 2020.
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