Non-obstetric abdominopelvic surgery during pregnancy is associated with a considerable materno-foetal complication rate related to the delayed diagnostic and therapeutic management and the severity of the underlying disease. Based on retrospective analysis of 9 laparoscopies performed during the second trimester of pregnancy between the months of January 1994 and October 1996 in the Gynaecology and Obstetrics Department of Hospital Bichat, the authors study the feasibility of this technique. They report 9 cases of abdominopelvic disease, in which laparoscopy allowed a diagnostic and therapeutic approach: 6 cases of adnexal disease, 2 appendicular syndromes and one diagnostic laparoscopy. The maternal and obstetric course was favourable in each case. Several cases of laparoscopic appendicectomy, cholecystectomy, and adnexal surgery during pregnancy have been published since 1990. The main reasons theoretically contraindicating laparoscopy after the first trimester of pregnancy are the risk of uterine injury and the foetal risk during creation of the pneumoperitoneum. Experimental data are limited, but the increased intra-abdominal pressure and the use of CO2 do not appear to have any harmful effects in animals (foetal lambs). By respecting a certain number of technical precautions, laparoscopy during the second trimester of pregnancy can constitute a legitimate diagnostic and therapeutic approach.
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Gynecol Obstet Fertil Senol
January 2025
Service d'obstétrique et médecine fœtale, CHRU de Nancy, Université de Lorraine, Nancy, France; INSERM U1254, Université de Lorraine, Vandœuvre-lès-Nancy, France. Electronic address:
Objective: To study the sexuality of pregnant women after Assisted Reproductive Technology (ART).
Methods: This was a prospective multicenter study based on two questionnaires: the Female Sexual Function Index (FSFI) and the Couple Satisfaction Index 32 (CSI 32). Two groups were compared: pregnancies following ART and spontaneous pregnancies.
J Affect Disord
January 2025
Department of Social and Behavioral Sciences, Yale School of Public Health, New Haven, CT 06510, USA; Center for Methods in Implementation and Prevention Sciences, Yale University, New Haven, CT 06510, USA. Electronic address:
Background: Maternal mental health can impact health care access and utilization for both the birthing parent and infant. We examined the association between prenatal depressive symptoms (episodic and chronic) and receipt of the postpartum 6-week visit and infant vaccinations in the first year postpartum.
Methods: Postpartum individuals (N = 672) who attended Expect With Me group prenatal care in Nashville, Tennessee and Detroit, Michigan completed surveys during the second and third trimesters of pregnancy, as well as 6- and 12- months postpartum.
Early Hum Dev
January 2025
Department of Obstetrics and Gynecology, Faculty of Medicine, Gazi University, Ankara, Turkey.
Purpose: To evaluate the use of anogenital distance (AGD) and genital tubercle length (GTL) between 11 and 13 + 6 weeks of gestation for fetal sex determination and to assess the impact of maternal androgen levels on these measurements.
Methods: A cross-sectional study was conducted from February to June 2017 with patients undergoing first trimester Down syndrome screening. Inclusion criteria were: (1) female age 18-49, (2) gestational age between 11 and 13 + 6 weeks, (3) optimal visualization of AGD and GTL, and (4) nonsmoking status.
Pharmaceutics
December 2024
Department of Obstetrics and Gynecology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto 14049-900, SP, Brazil.
: Fluoxetine (FLX) is the inhibitor of serotonin reuptake most prescribed in pregnant women with depression. This study evaluates the influence of gestational diabetes mellitus (GDM) on the enantioselective pharmacokinetics and transplacental distribution of FLX and its metabolite norfluoxetine (norFLX). : Ten pregnant women diagnosed with GDM (GDM group) were investigated in the third trimester of gestation after they achieved good glycemic control.
View Article and Find Full Text PDFNutrients
January 2025
Department of Maternal-Fetal Biology, National Research Institute for Child Health and Development, Tokyo 157-8535, Japan.
Background/objectives: The DNA methylation of neonatal cord blood can be used to accurately estimate gestational age. This is known as epigenetic gestational age. The greater the difference between epigenetic and chronological gestational age, the greater the association with an inappropriate perinatal fetal environment and development.
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