The AHCPR guideline on Treatment of Pressure Ulcers was released in December 1994. This guideline was based on the best available scientific evidence published between 1966 and May 1, 1993. Over 45,000 abstracts were reviewed in the literature analysis. Yet only 63.2% of the guideline recommendations were based on research of any type, and only 4.5% of the recommendations were supported by two or more randomized clinical trials. A more recent literature review (covering articles on pressure ulcers listed in the MEDLINE database between May 1, 1993, and December 1, 1996), revealed minimal advances in the scientific body of knowledge on pressure ulcer treatment. Advances have been made in the knowledge of electrical therapy and growth factors, and efforts are under way to enhance tools for monitoring healing. In an era of limited research funding, we need to carefully target our research efforts to maximize the advancement of our knowledge of pressure ulcer treatment. It is the hope of the NPUAP that this monograph will guide the research needed to ensure the most efficient utilization of funds to improve patient outcomes.
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Mai Dabas is Master's Degree Student, Department of Biomedical Engineering, Faculty of Engineering, Tel Aviv University, Tel Aviv, Israel. Suzanne Kapp, PhD, RN, is Clinical Associate Professor, School of Health Sciences, Faculty of Medicine, Dentistry and Health Sciences, Department of Nursing, The University of Melbourne, Melbourne, Australia; and National Manager Wound Prevention and Management, Regis Aged Care, Camberwell, Victoria, Australia. Amit Gefen, PhD, is Professor of Biomedical Engineering and the Herbert J. Berman Chair in Vascular Bioengineering, Department of Biomedical Engineering, Faculty of Engineering, Tel Aviv University, Tel Aviv, Israel; Skin Integrity Research Group (SKINT), University Centre for Nursing and Midwifery, Department of Public Health and Primary Care, Ghent University, Ghent, Belgium; and Department of Mathematics and Statistics and the Data Science Institute, Faculty of Sciences, Hasselt University, Hasselt, Belgium. Acknowledgments: This work was supported by a competitive grant from the Victorian Medical Research Acceleration Fund, with funding co-contribution from the Department of Nursing at the University of Melbourne, the Melbourne Academic Centre for Health, and Mölnlycke Health Care. This work was also partially supported by the Israeli Ministry of Science & Technology (Medical Devices Program grant no. 3-17421, awarded to Professor Amit Gefen in 2020). The authors thank Ms Carla Bondini for her assistance with data collection and management for this study and Mr Daniel Kapp for proofreading the manuscript. The authors have disclosed no other financial relationships related to this article. Submitted February 1, 2024; accepted in revised form April 16, 2024.
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Boas J. Wijker, BSc, is PhD Candidate, Department of Human Movement Sciences, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands. Sonja de Groot, PhD, is Associate Professor, Department of Human Movement Sciences, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, the Netherlands, and Senior Researcher, Amsterdam Rehabilitation Research Center, Reade, the Netherlands. Anne-Fleur Boertje, MSc, is Student, Department of Health Sciences, Vrije Universiteit Amsterdam. Jacinthe J. E. Adriaansen, MD, PhD, is Rehabilitation Physician, Amsterdam Rehabilitation Research Center. Wendy J. Achterberg-Warmer, MD, is Rehabilitation Physician, Amsterdam Rehabilitation Research Center. Amber Wighman, NP, is Nurse Practitioner, Triade Vitree, Lelystad, the Netherlands. Maurits W. van Tulder, PhD, MSc, is Dean, Department of Human Movement Sciences, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam. Thomas W. J. Janssen, PhD, is Full Professor, Department of Human Movement Sciences, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, and Senior Researcher, Amsterdam Rehabilitation Research Center. Johanna M. van Dongen, PhD, MSc, is Associate Professor, Department of Health Sciences, Vrije Universiteit Amsterdam.
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