Objective: To observe the effect of Yishen Xiezhuo Recipe (YSXZR) on glomerular mesangium cell (MSC) proliferation.
Methods: YSXZR was given to healthy and experimental CRF rats by gastrogavage, and the effect of their serum on MSC proliferation was observed.
Results: The serum could obviously inhibit the MSC proliferation. Compared with control rats to which physiological saline was given, the difference was significant (P < 0.01).
Conclusion: YSXZR could postpone CRF progress.
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