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Do Positive Psychosocial Factors Contribute to the Prediction of Coronary Artery Disease? A UK Biobank-Based Machine Learning Approach.
Eur J Prev Cardiol
July 2024
Department of Psychosomatic Medicine, University Hospital Basel and University of Basel, Basel, Switzerland.
Aim: Most prediction models for coronary artery disease (CAD) compile biomedical and behavioural risk factors, using linear multivariate models. This study explored the potential of integrating positive psychosocial factors (PPFs), including happiness, satisfaction with life, and social support, into conventional and machine learning-based CAD prediction models.
Methods: We included UK Biobank participants without CAD at baseline.
Association of Medication Adherence and Health Status in Heart Failure With Reduced Ejection Fraction: Insights From the CHAMP-HF Registry.
Circ Cardiovasc Qual Outcomes
September 2024
University of Missouri - Kansas City's Healthcare Institute for Innovation in Quality and Saint Luke's Mid America Heart Institute, Kansas City (R.S.E.-Z., M.M., D.D.N., M.N., J.A.S.).
Article Synopsis
- The study focuses on patients with heart failure with reduced ejection fraction (HFrEF) and the importance of adhering to prescribed medication guidelines to improve health status.
- Researchers analyzed the self-reported medication adherence of 3,495 outpatient participants over a 12-month period and found that nonadherent patients had worse health status at baseline and showed less improvement over time compared to those who followed their medication regimen.
- Additionally, for patients who improved their adherence, there was a trend toward better health outcomes, highlighting the significance of medication adherence in managing HFrEF.
Neuropilin-1 sex-dependently modulates inflammatory, angiogenic and osteogenic phenotypes in the calcifying valve interstitial cell.
Biochem Pharmacol
August 2024
Cardiovascular Translational Research, Navarrabiomed, Hospital Universitario de Navarra, Universidad Pública de Navarra, IdiSNA, Pamplona, Spain. Electronic address:
The pathological mechanisms underlying the sex-dependent presentation of calcific aortic stenosis (AS) remain poorly understood. We aim to analyse sex-specific responses of valve interstitial cells (VICs) to calcific environments and to identify new pathological and potentially druggable targets. First, VICs from stenotic patients were modelled using pro-calcifying media (HP).
View Article and Find Full Text PDFSix decades of cardiothoracic surgery: navigating new horizons, mending hearts with science and precision.
Indian J Thorac Cardiovasc Surg
May 2024
Division of Cardiothoracic Surgery, Star Hospitals, Road No. 10, Banjara Hills, Hyderabad, Telangana India 500034.
HTA community perspectives on the use of patient preference information: lessons learned from a survey with members of HTA bodies.
Int J Technol Assess Health Care
March 2024
Community and Patient Preference Research (CaPPRe), Sydney, NSW, Australia.
This research sought to assess whether and how patient preference (PP) data are currently used within health technology assessment (HTA) bodies and affiliated organizations involved in technology/drug appraisals and assessments. An exploratory survey was developed by the PP Project Subcommittee of the HTA International Patient and Citizen Involvement Interest Group to gain insight into the use, impact, and role of PP data in HTA, as well as the perceived barriers to its incorporation. Forty members of HTA bodies and affiliated organizations from twelve countries completed the online survey.
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