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Obesity Incidence According to Branched-Chain Amino Acid Intake and Plant-Based Diet Index Among Brazilian Adults: A Six-Year Follow-Up of the CUME Study.
Nutrients
January 2025
Laboratory of Energy Metabolism and Body Composition, Department of Nutrition and Health, Federal University of Viçosa, Viçosa 36570-900, Brazil.
Background: Few studies have evaluated the impact of branched-chain amino acid (BCAA) intake on the risk of obesity in adults. The results are contradictory, and the causality has not been explored. This study assessed the association between BCAA intake and obesity incidence among Brazilian adults and investigated the potential moderating role of the plant-based index (PDI) in this relationship.
View Article and Find Full Text PDFInfluenza Immunization in Very-Low-Birth-Weight Infants: Epidemiology and Long-Term Outcomes.
Vaccines (Basel)
January 2025
Airway Research Center North, German Center of Lung Research (DZL), 23562 Lübeck, Germany.
Background: Very-low-birth-weight infants (VLBWIs; birth weight < 1500 g) are at an increased risk of complicated influenza infection, which frequently includes pneumonia, encephalitis or even death. Data on influenza immunization and its outcome in VLBWIs are scarce. This study aimed to provide epidemiological data on influenza immunization for German VLBWIs and hypothesized that immunization would protect VLBWIs from infection-mediated neurodevelopmental impairment and preserves lung function at early school age.
View Article and Find Full Text PDFA novel frameshift variant in the gene is associated with recessive oculodentodigital dysplasia.
Ophthalmic Genet
January 2025
Department of Ophthalmology, Hospital das Clínicas - Empresa Brasileira de Serviços Hospitalares, Federal University of Pernambuco, Recife, Brazil.
Background: Oculodentodigital dysplasia (ODDD) is a rare syndrome that causes a constellation of facial, ophthalmic, dental, and limb abnormalities. Variants in the gap junction alpha-1 () gene have been described in patients with ODDD. Hereby we present the ocular manifestations in a patient with recessive ODDD due to a novel homozygous frameshift variant in .
View Article and Find Full Text PDFEconomic impact and clinical benefits of clinical pharmacy interventions: A six-year multi-center study using an innovative medication management tool.
PLoS One
January 2025
Cleopatra Hospital, Cleopatra Hospitals Group-(CHG), Cairo, Egypt.
Background: Increasing healthcare costs, particularly in Low- and Middle-Income Countries (LMICs) like Egypt, highlight the need for rational economic strategies. Clinical pharmacy interventions offer potential benefits by reducing drug therapy problems and associated costs, thereby supporting healthcare system sustainability.
Objective: This study evaluates the economic impact and clinical benefits of clinical pharmacy interventions in four tertiary hospitals in Egypt by implementing an innovative tool for medication management, focusing on cost avoidance and return on investment (ROI), while accounting for case severity and drug therapy problem (DTP) resolution.
The impact of long-term prescription policy on primary care utilisation and costs among hypertensive patients in China: a six-year longitudinal study.
J Glob Health
January 2025
School of Public Health, Fudan University, Shanghai, China.
Background: China has recently implemented a long-term prescription policy as a component of the family doctor system in order to strengthen chronic disease management. In this study, we evaluated the net policy impact on health care utilisation and costs at community health centres (CHCs) among hypertensive patients.
Methods: The study population included 164 857 hypertensive patients from a provincial capital city in Eastern China, with an average age of 69.
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